Evidence map›Paper›PMID 38785596›Full record

ArticleMicrobiology spectrum2024

Gut and respiratory tract microbiota in children younger than 12 months hospitalized for bronchiolitis compared with healthy children: can we predict the severity and medium-term respiratory outcome?

Raul Cabrera-Rubio, Cristina Calvo, Sonia Alcolea, María Bergia, Jorge Atucha, Francisco Pozo, Inmaculada Casas, María Arroyas, Maria Carmen Collado, Maria Luz García-García

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Respiratory diseases and the gut microbiota: an updated review.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Raul Cabrera-RubioDepartment of Biotechnology, Institute of Agrochemistry and Food Technology-National Research Council (IATA-CSIC), Paterna, Valencia, Spain.ORCID 0000-0003-3652-9558
Cristina CalvoPaediatric Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.ORCID 0000-0002-6503-3423
Sonia AlcoleaPaediatric Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.
María BergiaPaediatric Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.ORCID 0000-0002-6503-3423
Jorge AtuchaPaediatric Infectious Diseases Department, La Paz University Hospital, Madrid, Spain.
Francisco PozoRespiratory Viruses and Influenza Unit at the National Centre for Microbiology ISCIII (CIBERESP ISCIII), Madrid, Spain.
Inmaculada CasasRespiratory Viruses and Influenza Unit at the National Centre for Microbiology ISCIII (CIBERESP ISCIII), Madrid, Spain.ORCID 0000-0003-1840-1198
María ArroyasPaediatric Department, Severo Ochoa University Hospital, Leganés, Madrid, Spain.
Maria Carmen Collado *Department of Biotechnology, Institute of Agrochemistry and Food Technology-National Research Council (IATA-CSIC), Paterna, Valencia, Spain.ORCID 0000-0002-6204-4864
Maria Luz García-García *Translational Research Network in Paediatric Infectious Diseases (RITIP), Madrid, Spain.ORCID 0000-0003-4906-4227

Funding

Fondos FEDER. Spanish Health Resarch Fund PI18/00167 PI21/00377Fondos FEDER. Spanish Health Research Fund PI18/00009Merck & Co. | Merck Sharp and Dohme United Kingdom (MSD) Investigator studies program MISPSEICAP 2028-19SENP Beca Senior de investigación 2018SEPAR Ayuda a la invesatigación pediátrica 2020X Convocatoria proyectos de investigación Fundacion UAX
6 · The paper itself

Abstract

Growing evidence indicates that gut and respiratory microbiota have a potential key effect on bronchiolitis, mainly caused by respiratory syncytial virus (RSV). This was a prospective study of 96 infants comparing infants with bronchiolitis ( IMPORTANCE: Both the intestinal and respiratory microbiota of children with bronchiolitis, especially those with respiratory syncytial virus infection, are altered and differ from that of healthy children. The microbiota pattern in the acute episode could identify those children who will later have other respiratory episodes in the first year of life. Preventive measures could be adopted for this group of infants.

Indexed as

BronchiolitisGastrointestinal MicrobiomeRespiratory Syncytial Virus InfectionsBacteriaFecesFemaleHospitalizationHumansInfantInfant, NewbornMaleMicrobiotaNasopharynxProspective StudiesRespiratory SystemRNA, Ribosomal, 16SRNA, Ribosomal, 16Sgut microbiotainfantsnasopharyngeal microbiotarespiratory syncytial virusvirus

Identifiers

PMID38785596
PMCPMC11218511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.