Evidence map›Paper›PMID 38785557›Full record

ArticleCurrent issues in molecular biology2024

Development of MetaXplore: An Interactive Tool for Targeted Metagenomic Analysis.

Naima Bel Mokhtar, Elias Asimakis, Ioannis Galiatsatos, Amal Maurady, Panagiota Stathopoulou, George Tsiamis

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  8. Bioinformatics Research in Bacterial Genomics and Metagenomics.Current issues in molecular biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naima Bel MokhtarLaboratory of Systems Microbiology and Applied Genomics, Department of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0002-7094-5849
Elias AsimakisLaboratory of Systems Microbiology and Applied Genomics, Department of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0001-9109-1750
Ioannis GaliatsatosLaboratory of Systems Microbiology and Applied Genomics, Department of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0002-6030-7798
Amal MauradyLaboratory of Innovative Technologies, National School of Applied Sciences of Tangier, Abdelmalek Essaâdi University, Tanger 93000, Morocco.ORCID 0000-0001-9298-717X
Panagiota StathopoulouLaboratory of Systems Microbiology and Applied Genomics, Department of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0003-3941-0990
George TsiamisLaboratory of Systems Microbiology and Applied Genomics, Department of Sustainable Agriculture, University of Patras, 30100 Agrinio, Greece.ORCID 0000-0001-5616-8505

Funding

Hellenic Foundation for Research and Innovation 423
6 · The paper itself

Abstract

Over the last decades, the analysis of complex microbial communities by high-throughput sequencing of marker gene amplicons has become routine work for many research groups. However, the main challenges faced by scientists who want to make use of the generated sequencing datasets are the lack of expertise to select a suitable pipeline and the need for bioinformatics or programming skills to apply it. Here, we present MetaXplore, an interactive, user-friendly platform that enables the discovery and visualization of amplicon sequencing data. Currently, it provides a set of well-documented choices for downstream analysis, including alpha and beta diversity analysis, taxonomic composition, differential abundance analysis, identification of the core microbiome within a population, and biomarker analysis. These features are presented in a user-friendly format that facilitates easy customization and the generation of publication-quality graphics. MetaXplore is implemented entirely in the R language using the Shiny framework. It can be easily used locally on any system with R installed, including Windows, Mac OS, and most Linux distributions, or remotely via a web server without bioinformatic expertise. It can also be used as a framework for advanced users who can modify and expand the tool.

Indexed as

amplicon data analysisdata visualizationdifferential abundancediversity analysismicrobial profilingshiny frameworktaxonomic composition

Identifiers

PMID38785557
PMCPMC11120546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.