Evidence map›Paper›PMID 38785503›Full record

ArticleCurrent issues in molecular biology2024

Açaí (

Katia Regina Assunção Borges, Lais Araújo Souza Wolff, Marcos Antonio Custódio Neto da Silva, Allysson Kayron de Carvalho Silva, Carmem Duarte Lima Campos, Franscristhiany Silva Souza, Amanda Mara Teles, André Álvares Marques Vale, Henrique Pascoa, Eliana Martins Lima and 6 more

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Katia Regina Assunção BorgesNortheast Biotechnology Postgraduate Program, Renorbio, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.ORCID 0000-0002-8642-5418
Lais Araújo Souza WolffAdult Health Master's Postgraduate Program-PPGSAD, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.
Marcos Antonio Custódio Neto da SilvaMedicine Course, Federal University of Maranhao, Imperatriz 65915-060, Maranhao, Brazil.ORCID 0000-0003-2748-1564
Allysson Kayron de Carvalho SilvaNortheast Biotechnology Postgraduate Program, Renorbio, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.ORCID 0000-0001-9792-8486
Carmem Duarte Lima CamposPostgraduate Program in Health Sciences, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.
Franscristhiany Silva SouzaPostgraduate Program in Biodiversity and Biotechnology of the Bionorte Network, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.
Amanda Mara TelesProfessional Postgradualte Program in Animal Health Defense, State University of Maranhão, Av. Oeste Externa, 2220-São Cristóvão, São Luís 65010-120, Maranhao, Brazil.ORCID 0000-0002-5068-4696
André Álvares Marques ValePostgraduate Program in Health Sciences, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.
Henrique PascoaFarmatec Laboratory at the Federal University of Goiás, Campus Samambaia da UFG, Goiânia 74690-631, Goiás, Brazil.ORCID 0000-0003-2542-6879
Eliana Martins LimaFarmatec Laboratory at the Federal University of Goiás, Campus Samambaia da UFG, Goiânia 74690-631, Goiás, Brazil.ORCID 0000-0003-1231-5803
Eduardo Martins de SousaGraduate Program in Biosciences Applied to Health, CEUMA Universitity, São Luís 65075-120, Maranhão, Brazil.ORCID 0000-0002-2506-169X
Ana Clara Silva NunesCoordination of the Chemical Engineering course, Center for Exact Sciences and Technology, Federal University of Maranhao (UFMA), São Luís 65080-085, Maranhão, Brazil.
Rui M Gil da CostaPostgraduate Program in Health Sciences, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.ORCID 0000-0002-2151-2449
Ana Isabel Faustino-RochaCentre for the Research and Technology of Agro-Environmental and Biological Sciences, Universidade de Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal.ORCID 0000-0001-5572-6317
Rafael Cardoso CarvalhoPostgraduate Program in Health Sciences, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.ORCID 0000-0001-7073-8308
Maria do Desterro Soares Brandão NascimentoNortheast Biotechnology Postgraduate Program, Renorbio, Federal University of Maranhao (UFMA), Avenida dos Portugueses, 1966 Bacanga, Saõ Luis 65080-085, Maranhao, Brazil.ORCID 0000-0003-2783-362X

Funding

Fundação para a Ciência e Tecnologia https://doi.org/10.54499/UIDB/04033/2020
6 · The paper itself

Abstract

This study explores a nanoemulsion formulated with açaí seed oil, known for its rich fatty acid composition and diverse biological activities. This study aimed to characterise a nanoemulsion formulated with açaí seed oil and explore its cytotoxic effects on HeLa and SiHa cervical cancer cell lines, alongside assessing its antioxidant and toxicity properties both in vitro and in vivo. Extracted from fruits sourced in Brazil, the oil underwent thorough chemical characterization using gas chromatography-mass spectrometry. The resulting nanoemulsion was prepared and evaluated for stability, particle size, and antioxidant properties. The nanoemulsion exhibited translucency, fluidity, and stability post centrifugation and temperature tests, with a droplet size of 238.37, PDI -9.59, pH 7, and turbidity 0.267. In vitro assessments on cervical cancer cell lines revealed antitumour effects, including inhibition of cell proliferation, migration, and colony formation. Toxicity tests conducted in cell cultures and female Swiss mice demonstrated no adverse effects of both açaí seed oil and nanoemulsion. Overall, açaí seed oil, particularly when formulated into a nanoemulsion, presents potential for cancer treatment due to its bioactive properties and safety profile.

Indexed as

açaí oilcervical cancerEuterpe oleracea Mart.nanoemulsion

Identifiers

PMID38785503
PMCPMC11120212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.