Evidence map›Paper›PMID 38785498›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Multidisciplinary and Tailored Treatment of Locally Advanced Breast Cancer in Progression during Neoadjuvant Chemotherapy: Case Report.

Letizia Cuniolo, Marco Gipponi, Federica Murelli, Francesca Depaoli, Chiara Cornacchia, Simonetta Franchelli, Marianna Pesce, Elena Ronda, Stefano Picardi, Raquel Diaz and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Letizia CunioloDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.ORCID 0009-0003-3826-874X
Marco GipponiBreast Surgery Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Federica MurelliDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.
Francesca DepaoliBreast Surgery Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Chiara CornacchiaBreast Surgery Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Simonetta FranchelliBreast Surgery Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Marianna PesceBreast Surgery Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Elena RondaDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.
Stefano PicardiDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.
Raquel DiazDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0001-5764-6804
Francesca PoggioDepartment of Medical Oncology, U.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Daniele FriedmanDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.
Franco De CianDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.
Piero FregattiDepartment of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-1279-5299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locally advanced breast cancer (LABC) is a complex disease that requires a multidisciplinary approach. Neoadjuvant chemotherapy (NAC) is usually performed in order to achieve loco-regional radical resection; although its importance in the multidisciplinary approach to LABC is well recognized, a small number of patients show Progressive Disease (PD). No standard salvage treatment (ST) has been defined and different strategies can be adopted, such as second-line systemic therapies, radiation therapy, and surgery. Herein, a case of LABC in PD during NAC is reported with a literature review, with the aim of highlighting the importance of a tailored multidisciplinary treatment for each patient.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyAntineoplastic Combined Chemotherapy ProtocolsDisease ProgressionFemaleHumansMiddle Agedlocally advanced breast cancer (LABC)progressive disease (PD)salvage treatment (ST)

Identifiers

PMID38785498
PMCPMC11119312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.