Evidence map›Paper›PMID 38785489›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Parenteral Nutrition in Palliative Cancer Care: Detrimental, Futile, or Beneficial?

Erik Torbjørn Løhre, Tora Skeidsvoll Solheim, Gunnhild Jakobsen, Ola Magne Vagnildhaug, Terese Louise Schmidberger Karlsen, Ragnhild Hansdatter Habberstad, Trude Rakel Balstad, Morten Thronæs

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erik Torbjørn LøhreCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.
Tora Skeidsvoll SolheimCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.ORCID 0000-0002-2565-8437
Gunnhild JakobsenCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.
Ola Magne VagnildhaugCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.
Terese Louise Schmidberger KarlsenCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.
Ragnhild Hansdatter HabberstadCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.
Trude Rakel BalstadDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, 7030 Trondheim, Norway.ORCID 0000-0002-5715-4268
Morten ThronæsCancer Clinic, St. Olavs Hospital, Trondheim University Hospital, 7030 Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palliative cancer care patients may live for a long time, but malnutrition worsens the prognosis. Parenteral nutrition (PN) is suitable for replenishing a calorie deficit, but its advantages and tolerance late in the cancer trajectory are debated. We examined symptom development in hospitalized patients with and without PN. A total of 21 palliative cancer care patients receiving PN and 155 palliative cancer care patients not receiving PN during hospitalization in a specialized unit were retrospectively compared. We studied symptom intensity at admission, symptom relief during the hospital stay, and survival. The patients had locally advanced or metastatic cancer, a mean age of 70 years, and their median ECOG performance status was III. Symptom burden at admission was similar in the compared groups. Symptom relief during hospitalization was also similar. However, patients already on PN at admission reported more nausea and patients receiving PN during hospitalization reported better nausea relief compared to patients not receiving this intervention. Overall median survival was less than two months and similar in the compared groups. Based on a limited number of observations and a suboptimal study design, we were not able to demonstrate an increased symptom burden for palliative cancer care patients receiving PN late in the disease trajectory.

Indexed as

NeoplasmsPalliative CareParenteral NutritionAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective Studiesnauseapalliative cancer careparenteral nutritionsymptom burdentolerance

Identifiers

PMID38785489
PMCPMC11120543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.