Evidence map›Paper›PMID 38785430›Full record

ArticleMicrobiology spectrum2024

Altered gut microbiota is associated with the formation of occult hepatitis B virus infection.

Bochao Liu, Hualong Yang, Qiao Liao, Min Wang, Jieting Huang, Ru Xu, Zhengang Shan, Huishan Zhong, Tingting Li, Chengyao Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bochao Liu *Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.ORCID 0000-0003-3539-6618
Hualong Yang *Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qiao LiaoInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Min WangInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jieting HuangInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Ru XuInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhengang ShanInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Huishan ZhongInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Tingting LiDepartment of Transfusion Medicine, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.ORCID 0000-0001-5727-2179
Chengyao LiDepartment of Transfusion Medicine, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.ORCID 0000-0002-2087-873X
Yongshui FuInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.ORCID 0000-0002-2199-2980
Xia RongInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, Guangdong, China.ORCID 0000-0002-2463-6340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV), a common blood transmission pathogen worldwide, can lead to viral hepatitis, cirrhosis, liver cancer, and other liver diseases. In particular, occult hepatitis B virus infection (OBI) may be caused by an immune response leading to suppressed virus replication. Gut microbiota can change the immunity status of the human body and, therefore, affect the replication of HBV. Thus, to identify whether there are differences in gut microbiota between HBV carriers and OBI carriers, we collected fecal samples from 18 HBV carriers, 24 OBI blood donors, and also 20 healthy blood donors as negative control. After 16S sequencing, we found that the abundance of

Indexed as

FecesGastrointestinal MicrobiomeHepatitis BHepatitis B virusAdultBacteriaBlood DonorsCarrier StateDNA, ViralFemaleHepatitis B Surface AntigensHumansMaleMiddle AgedRNA, Ribosomal, 16SVirus ReplicationDNA, ViralHepatitis B Surface AntigensRNA, Ribosomal, 16S16S sequencingFaecalibacteriumgut microbiotaoccult hepatitis B virus infectionSubdoligranulum

Identifiers

PMID38785430
PMCPMC11218497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.