Trial reportThe Journal of urology2024
Comparing Magnetic Resonance Imaging and Prostate-Specific Membrane Antigen-Positron Emission Tomography for Prediction of Extraprostatic Extension of Prostate Cancer and Surgical Guidance: A Prospective Nonrandomized Clinical Trial.
Trial report in The Journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- [European journal of nuclear medicine and molecular imaging · 2026Article
- Integrating clinical and technological perspectives to enhance predictive modeling in prostate cancer surgery.Prostate cancer and prostatic diseases · 2025Article
- Local staging of de novo prostate cancer using mpMRI, PSMA-PET and PSMA-PET/mpMRI - a comparative study.EJNMMI research · 2025Article
- Impact ofDiagnostics (Basel, Switzerland) · 2025Article
- Defining the Role of Postoperative Radio-Hormone Therapy in Prostate Cancer.Current oncology reports · 2025Review
- The Role of PSMA PET Imaging in Prostate Cancer: Current Applications and Future Directions.Current urology reports · 2025Review
- PSMA PET/CT for prostate cancer diagnosis: current applications and future directions.Journal of cancer research and clinical oncology · 2025Review
- Update on PSMA-based Prostate Cancer Imaging.Seminars in nuclear medicine · 2024Review
- Extracapsular extension risk assessment using an artificial intelligence prostate cancer mapping algorithm.BJUI compass · 2024Article
- Round up.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
purposeSurvivors of surgically managed prostate cancer may experience urinary incontinence and erectile dysfunction. Our aim was to determine if MATERIALS AND
methodsWe prospectively enrolled 50 patients at risk for extraprostatic extension (EPE) who were scheduled for prostatectomy. After mpMRI and PSMA-PET images were read for EPE prediction, surgeons prospectively answered questionnaires based on mpMRI and PSMA-PET scans on the decision for nerve-sparing or nonnerve-sparing approach. Final whole-mount pathology was the reference standard. Sensitivity, specificity, positive predictive value, negative predictive value, and receiver operating characteristic curves were calculated and McNemar's test was used to compare imaging modalities.
resultsThe median age and PSA were 61.5 years and 7.0 ng/dL. The sensitivity for EPE along the posterior neurovascular bundle was higher for PSMA-PET than mpMRI (86% vs 57%,
conclusionsPSMA-PET scan was more sensitive than mpMRI for EPE along the neurovascular bundles and improved surgical decisions for nerve-sparing approach. Further study of PSMA-PET for surgical guidance is warranted in the unfavorable intermediate-risk or worse populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.