Evidence map›Paper›PMID 38784596›Full record

ArticleFrontiers in public health2024

Investing in health preparedness, response and resilience: a genomics costing tool focused on next generation sequencing.

Oluwatosin Wuraola Akande, Babak Afrough, Maria Amante, Lisa Carter, Jane Cunningham, Noah Clayton Hull, Leena Inamdar, Alexandr Jaguparov, Marco Marklewitz, Biran Musul and 9 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. From DNA to Big Data: NGS Technologies and Their Applications.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Oluwatosin Wuraola AkandeDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Babak AfroughNew Variant Assessment Platform, UK Health Security Agency, London, United Kingdom.
Maria AmanteInfectious Hazard Management, World Health Organization Regional Office for Europe, Copenhagen, Denmark.
Lisa CarterDepartment of Country Readiness Strengthening, World Health Organization Lyon Office, Lyon, France.
Jane CunninghamDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Noah Clayton HullGlobal Health, Association of Public Health Laboratories, Bethesda, MD, United States.
Leena InamdarNew Variant Assessment Platform, UK Health Security Agency, London, United Kingdom.
Alexandr JaguparovInfectious Hazard Management, World Health Organization Regional Office for Europe, Copenhagen, Denmark.
Marco MarklewitzGenomics and Sequencing, FIND, Geneva, Switzerland.
Biran MusulInfectious Hazard Management, World Health Organization Regional Office for Europe, Copenhagen, Denmark.
Ashley NorbergGlobal Health, Association of Public Health Laboratories, Bethesda, MD, United States.
Dmitriy I PereyaslovDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Angela Lee PoatesGlobal Health, Association of Public Health Laboratories, Bethesda, MD, United States.
Gina SamaanDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Anita SureshGenomics and Sequencing, FIND, Geneva, Switzerland.
Swapna UplekarGenomics and Sequencing, FIND, Geneva, Switzerland.
Aude WilhemNew Variant Assessment Platform, UK Health Security Agency, London, United Kingdom.
Joanna Salvi Le Garrec ZwetyengaInfectious Hazard Management, World Health Organization Regional Office for Europe, Copenhagen, Denmark.
Toni WhistlerTechnical Advice and Partnership Department, The Global Fund to Fight AIDS, Tuberculosis and Malaria, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

The world has seen unprecedented gains in the global genomic surveillance capacities for pathogens with pandemic and epidemic potential within the last 4 years. To strengthen and sustain the gains made, WHO is working with countries and partners to implement the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022-2032. A key technical product developed through these multi-agency collaborative efforts is a genomics costing tool (GCT), as sought by many countries. This tool was developed by five institutions - Association of Public Health Laboratories, FIND, The Global Fund to Fight AIDS, Tuberculosis and Malaria, UK Health Security Agency, and the World Health Organization. These institutions developed the GCT to support financial planning and budgeting for SARS-CoV-2 next-generation sequencing activities, including bioinformatic analysis. The tool costs infrastructure, consumables and reagents, human resources, facility and quality management. It is being used by countries to (1) obtain costs of routine sequencing and bioinformatics activities, (2) optimize available resources, and (3) build an investment case for the scale-up or establishment of sequencing and bioinformatics activities. The tool has been validated and is available in English and Russian at https://www.who.int/publications/i/item/9789240090866. This paper aims to highlight the rationale for developing the tool, describe the process of the collaborative effort in developing the tool, and describe the utility of the tool to countries.

Indexed as

COVID-19GenomicsHigh-Throughput Nucleotide SequencingSARS-CoV-2Civil DefenseComputational BiologyGlobal HealthHumansPandemicscost-analysiscosting toolgenomic sequencinggenomic surveillanceinfectious diseasenext-generation sequencing

Identifiers

PMID38784596
PMCPMC11111868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.