Evidence map›Paper›PMID 38784504›Full record

ArticleEthiopian journal of health sciences2023

Colistin Susceptibility Testing by Colistin Broth Disk Elution MIC Method among Carbapenem-resistant Gram-negative Blood Culture Clinical Isolates in a Tertiary Care Setting, East Delhi, India.

Kirti Nirmal, Narendra Pal Singh, Krishna Sarkar, Nisha Goyal, Seema Gangar, Aditya Nath Dwivedi

Abstract read
In one paragraph

Article in Ethiopian journal of health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Kirti NirmalDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.
Narendra Pal SinghDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.
Krishna SarkarDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.
Nisha GoyalDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.
Seema GangarDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.
Aditya Nath DwivediDepartment of Microbiology University College of Medical Sciences and Guru Tag Bahadur Hospital Delhi 110095.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antibiotic resistance is a growing concern for bloodstream infections (BSIs), especially with the emergence of multidrug-resistant (MDR) gram-negative bacteria. In this study, we aimed to assess the pattern of colistin susceptibility using the colistin broth disc elution (CBDE) method among carbapenem-resistant gram-negative clinical isolates from blood cultures in a high burden tertiary healthcare setting in East Delhi. Methods: A total of 106 carbapenem-resistant gram-negative clinical isolates were tested. The most common isolates were Klebsiella pneumoniae, Escherichia coli, Enterobacter species, and Klebsiella oxytoca by CBDE method. Result: All the carbapenem resistant gram-negative bacterial blood culture isolates showed intermediate colistin susceptibility. This was statistically significant by chi-square test (p<0.5). Conclusion: This study highlights the need to monitor colistin resistance trends in the face of increasing antimicrobial resistance. Accurate surveillance of emerging colistin resistance is crucial for effective management of BSIs caused by carbapenem-resistant gram-negative bacteria.

Indexed as

Anti-Bacterial AgentsCarbapenemsColistinGram-Negative BacteriaMicrobial Sensitivity TestsBacteremiaBlood CultureDrug Resistance, Multiple, BacterialEscherichia coliGram-Negative Bacterial InfectionsHumansIndiaKlebsiella pneumoniaeTertiary Care CentersTertiary Health CareAnti-Bacterial AgentsCarbapenemsColistinCarbapenem-resistantColistin broth disk elution (CBDE)Gram-negative

Identifiers

PMID38784504
PMCPMC11111212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.