Evidence map›Paper›PMID 38784434›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2024

Early Real-World Patient and Staff Experience with an Intracanalicular Dexamethasone Insert.

Lisa Nijm, Cynthia Matossian, Michelle K Rhee, John D Stephens, Maria E Rosselson, Parag A Majmudar, Subba Rao Gollamudi, Ravi H Patel, Aditi Bauskar, Alyssa Montieth and 5 more

Erratum issuedAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Lisa NijmWarrenville EyeCare and LASIK, Warrenville, IL, USA.
Cynthia MatossianCM Associates, LLC, New Hope, PA, USA.ORCID 0000-0003-4119-5230
Michelle K RheeIcahn School of Medicine at Mount Sinai, New York, NY, USA.
John D StephensTyson Eye, Fort Myers, FL, USA.
Maria E RosselsonChicago Cornea Consultants, Ltd, Chicago, IL, USA.
Parag A MajmudarChicago Cornea Consultants, Ltd, Chicago, IL, USA.
Subba Rao GollamudiEye Specialty Group, Memphis, TN, USA.ORCID 0000-0003-1261-8521
Ravi H PatelEye Associates of Central Texas, Round Rock, TX, USA.
Aditi BauskarOcular Therapeutix, Inc, Bedford, MA, USA.ORCID 0000-0001-7595-6267
Alyssa MontiethOcular Therapeutix, Inc, Bedford, MA, USA.
Srilatha VantipalliOcular Therapeutix, Inc, Bedford, MA, USA.
Andrea GibsonOcular Therapeutix, Inc, Bedford, MA, USA.
Jamie Lynne MetzingerOcular Therapeutix, Inc, Bedford, MA, USA.
Michael H GoldsteinOcular Therapeutix, Inc, Bedford, MA, USA.
Rabia Gurses OzdenOcular Therapeutix, Inc, Bedford, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate both the early experience of real-world patients treated with dexamethasone ophthalmic insert (0.4 mg; DEXTENZA Patients and Methods: This was a cross-sectional survey study of 23 cataract practices in the United States. Respondents were patients and practice staff who had experience with DEX following cataract surgery. Both patients and practice staff completed an online survey. Descriptive statistics summarized the survey responses to portray the experience of the respondents. Results: Surveys were completed by 62 patients and 19 practice staff. Almost all patients (93%) were satisfied or extremely satisfied with DEX. Patients highly preferred DEX (93%) to topical steroid drops (7%) based on past experiences with topical steroid drops. Most practice staff (95%) were satisfied or highly satisfied with DEX, reporting a 45% reduction in time spent educating patients on postoperative drop use and a 46% decrease in time spent addressing calls from pharmacies regarding postoperative medications. Conclusion: Incorporating the DEX insert into clinical practice in cataract surgery practices can improve patient adherence, while potentially providing significant savings to practices in terms of time spent educating patients and responding to patient and pharmacy call-backs.

Indexed as

hands-free therapyintracanalicular dexamethasone insertocular inflammationocular painphacoemulsificationsustained-release drug delivery

Identifiers

PMID38784434
PMCPMC11114144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.