Evidence map›Paper›PMID 38784403›Full record

ArticlePeerJ2024

Clinical value of serum polyunsaturated fatty acids in patients with gastric polyps.

Nan Li, Qiliu Qian, Jun Ouyang, Mingyue Hu, Juan Liu, Hailu Wu, Ruihua Shi, Shiya Zheng

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nan LiZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Qiliu QianZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Jun OuyangZhenjiang Hospital Affiliated to Nanjing University of Chinese Medicine, Zhenjiang, China.
Mingyue HuZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Juan LiuZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Hailu WuZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Ruihua ShiZhongda Hospital Affiliated to Southeast University, Department of Gastroenterology, Nanjing, China.
Shiya ZhengZhongda Hospital Affiliated to Southeast University, Department of Oncology, Nanjing, China.

Funding

National Natural Science Foundation of China Youth FoundationOpen Project of Zhenjiang Traditional Chinese Medicine Spleen and Stomach Disease Clinical Medicine Research Center (Zhenjiang Hospital Affiliated to Nanjing University of Chinese Medicine)
6 · The paper itself

Abstract

Polyunsaturated fatty acids (PUFAs) are vital nutrients in human physiology and are implicated in various chronic diseases. However, the relationship between PUFAs and gastric polyps remains unclear. This study employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to assess PUFA levels in the serum of 350 patients, along with analyzing the ω-6 to ω-3 ratio. The results revealed significant differences in the levels of C16:1, C18:1, C18:2, α-C18:3, γ-C18:3, C20:1, C20:4, C20:5, ω-3-C22:5, ω-6-C22:5, and C22:6, as well as ω-6 to ω-3 ratio between the control and gasteic polyp groups. Moreover, setting the threshold for ω-6: ω-3 at 10 revealed a close correlation between polyp occurrence and this ratio. These findings suggest that PUFAs and the ω-6 to ω-3 ratio hold promise as potential early screening markers for gastric polyps. However, further research is imperative to elucidate the underlying mechanisms and therapeutic potential of PUFAs in managing gastric polyps.

Indexed as

Fatty Acids, Omega-3Fatty Acids, Omega-6Fatty Acids, UnsaturatedTandem Mass SpectrometryAdenomatous PolypsAdultAgedBiomarkersCase-Control StudiesChromatography, LiquidFemaleHumansMaleMiddle AgedStomach NeoplasmsBiomarkersFatty Acids, Omega-3Fatty Acids, Omega-6Fatty Acids, UnsaturatedGastric polypsLiquid chromatography-tandem mass spectrometryPolyunsaturated fatty acids

Identifiers

PMID38784403
PMCPMC11114109

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.