Evidence map›Paper›PMID 38784091›Full record

ArticleFrontiers in neuroscience2024

Association between serum potassium and Parkinson's disease in the US (NHANES 2005-2020).

Xue Zhou, Jingtong Zhao, Yang Liu, Xiaozhou Sun, Xuefeng Li, Jixiang Ren, Qingjie Li, Dong Han, Ting Pan, Yingqi Shi and 2 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xue Zhou *Changchun University of Chinese Medicine, Changchun, China.
Jingtong Zhao *Changchun Central Hospital, Changchun, China.
Yang LiuChangchun University of Chinese Medicine, Changchun, China.
Xiaozhou SunCenter of Children's Clinic, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Xuefeng LiChangchun University of Chinese Medicine, Changchun, China.
Jixiang RenThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Qingjie LiThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Dong HanChangchun University of Chinese Medicine, Changchun, China.
Ting PanThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Yingqi ShiChangchun University of Chinese Medicine, Changchun, China.
Dalong WuThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.
Xinhua ChenThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Evaluating the correlation between serum potassium and Parkinson's disease (PD) in US adults. Methods: A cross-sectional study was conducted on 20,495 adults aged 40 years or older using NHANES data from 2005 to 2020. The study utilized one-way logistic regression and multifactorial logistic regression to examine the correlation between serum potassium levels and PD. Additionally, a smoothed curve fitting approach was employed to assess the concentration-response relationship between serum potassium and PD. Stratified analyses were carried out to investigate potential interactions between serum potassium levels and PD with variables such as age, sex, race, marital status, education, BMI, smoking and medical conditions like coronary, stroke, diabetes, hypertension, and hypercholesterolemia. Results: In this study, a total of 20,495 participants, comprising 403 PD and 20,092 non-PD individuals, were included. After adjusted for covariates, multivariable logistic regression revealed that high serum potassium level was an independent risk factor for PD (OR:1.86, 95% CI:1.45 ~ 2.39, Conclusion: Serum potassium levels are elevated in patients with Parkinson's disease compared to non-PD patients. Additional prospective studies are required to explore the significance of serum potassium levels in individuals with Parkinson's disease.

Indexed as

cross-sectional studyneurodegenerationNHANESParkinson’s diseaseserum potassium

Identifiers

PMID38784091
PMCPMC11111918

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.