Evidence map›Paper›PMID 38783320›Full record

ArticleMicrobial cell factories2024

Fermentative aminopyrrolnitrin production by metabolically engineered Corynebacterium glutamicum.

Virginia Ryandini Melati Putri, Min-Hee Jung, Ji-Young Lee, Mi-Hyang Kwak, Theavita Chatarina Mariyes, Anastasia Kerbs, Volker F Wendisch, Hee Jeong Kong, Young-Ok Kim, Jin-Ho Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell factories, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Metabolic Engineering ofJournal of microbiology and biotechnology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Virginia Ryandini Melati Putri *Department of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea.
Min-Hee Jung *Department of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea.
Ji-Young LeeDepartment of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea.
Mi-Hyang KwakDepartment of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea.
Theavita Chatarina MariyesDepartment of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea.
Anastasia KerbsFaculty of Biology and Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
Volker F WendischFaculty of Biology and Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
Hee Jeong KongBiotechnology Research Division, National Institute of Fisheries Science, Busan, 46083, Republic of Korea.
Young-Ok KimBiotechnology Research Division, National Institute of Fisheries Science, Busan, 46083, Republic of Korea.
Jin-Ho LeeDepartment of Food Science & Biotechnology, BB21+, Kyungsung University, Busan, 48434, Republic of Korea. jhlee83@ks.ac.kr.

Funding

National Institute of Fisheries Science, Ministry of Oceans and Fisheries, Korea R2024019
6 · The paper itself

Abstract

Aminopyrrolnitrin (APRN), a natural halogenated phenylpyrrole derivative (HPD), has strong antifungal and antiparasitic activities. Additionally, it showed 2.8-fold increased photostability compared to pyrrolnitrin, a commercially available HPD with antimicrobial activity. For microbial production of APRN, we first engineered anthranilate phosphoribosyltransferase encoded by trpD from Corynebacterium glutamicum, resulting in a TrpD

Indexed as

Corynebacterium glutamicumMetabolic EngineeringBacterial ProteinsEscherichia coliFermentationOxidoreductasesPyrrolnitrinTryptophanBacterial ProteinsOxidoreductasesPyrrolnitrinTryptophantryptophan halogenase7-Chloro-l-tryptophanAminopyrrolnitrinCorynebacterium glutamicumMicrobial productionMonodechloroaminopyrrolnitrinMutant TrpD

Identifiers

PMID38783320
PMCPMC11112847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.