ArticleBMC neurology2024
Ectopic cervical thymoma in myasthenia gravis: a case report.
Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- An Exceptional Preaortic Ectopic Type B2 Thymoma as the Cause of Refractory Myasthenia Gravis: A Case Report.Cureus · 2026Article
- Ectopic Cervical Thymoma with Myasthenia Gravis and Pure Red Cell Aplasia: A Case Report.Surgical case reports · 2026Article
- Article
- Detecting ectopic thymus in thymoma-associated myasthenia gravis through flow cytometry analysis of CD3Annals of medicine and surgery (2012) · 2025Article
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Authors and funding
3 authors.
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Abstract
backgroundEctopic cervical thymoma (ECT) is an extremely rare tumor, especially in association with myasthenia gravis (MG). CASE PRESENTATION: We report a case of myasthenia gravis with an ectopic thymoma in the neck, whose myasthenic symptoms significantly improved after complete removal of the mass. A 55-year-old woman with generalized myasthenia gravis (MG) experienced worsening neuromuscular weakness after abruptly discontinuing pyridostigmine. Testing revealed acetylcholine receptor-antibody (AChR-Ab) positivity and a cervical mass initially thought to be thyroid or parathyroid was identified as a thymoma, type A. Post-surgery and radiation therapy, her myasthenic symptoms improved significantly with less prednisone and pyridostigmine requirements over time and no need for additional immunotherapies.
conclusionsDiagnosing ECTs is challenging due to rarity, atypical locations, and inconclusive fine needle aspiration cytology (FNAC) results, often misinterpreted as thyroid or parathyroid lesions. As proper management of patients with MG, including thymectomy, offers favorable clinical outcomes such as significant improvement in myasthenic complaints and reduced immunosuppressive medication requirements, clinicians should be vigilant of the ectopic locations of thymomas to ensure timely diagnosis and intervention.
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