Evidence map›Paper›PMID 38783005›Full record

ArticleCommunications biology2024

The integration of metabolic and proteomic data uncovers an augmentation of the sphingolipid biosynthesis pathway during T-cell differentiation.

Toshio Kanno, Ryo Konno, Masaru Sato, Atsushi Kurabayashi, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K Asou, Junichiro Ohzeki and 5 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. LC-MS-Based Analytical Strategies for Ganglioside Profiling.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Toshio KannoDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.ORCID 0000-0002-7586-8723
Ryo KonnoDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Masaru SatoDepartment of Research and Development, Kazusa DNA Research Institutes, Kisarazu, Japan.
Atsushi KurabayashiDepartment of Research and Development, Kazusa DNA Research Institutes, Kisarazu, Japan.
Keisuke MiyakoDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Takahiro NakajimaDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Satoru YokoyamaDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Shigemi SasamotoDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Hikari K AsouDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Junichiro OhzekiDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Yoshinori HasegawaDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Kazutaka IkedaDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.
Yusuke KawashimaDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.ORCID 0000-0002-9779-8199
Osamu OharaDepartment of Applied Genomics Kazusa DNA Research Institute, Kisarazu, Chiba, Japan.ORCID 0000-0002-3328-9571
Yusuke EndoDepartment of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan. endo@kazusa.or.jp.ORCID 0000-0002-7223-1938

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT) Jp18H04665Ministry of Education, Culture, Sports, Science and Technology (MEXT) Jp20H03455Ministry of Education, Culture, Sports, Science and Technology (MEXT) Jp20K21618Ministry of Education, Culture, Sports, Science and Technology (MEXT) Jp21K15476
6 · The paper itself

Abstract

Recent studies have highlighted the significance of cellular metabolism in the initiation of clonal expansion and effector differentiation of T cells. Upon exposure to antigens, naïve CD4

Indexed as

Cell DifferentiationMetabolomicsProteomicsSphingolipidsAnimalsMiceMice, Inbred C57BLSphingolipids

Identifiers

PMID38783005
PMCPMC11116545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.