ReviewNature reviews. Disease primers2024
Carpal tunnel syndrome.
Review in Nature reviews. Disease primers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Comparative Study of Ultrasound-Guided Corticosteroid Injection with Acupotomy Release Versus Injection Alone in Carpal Tunnel Syndrome: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Ultrasound-guided needle knife release of the transverse carpal ligament for carpal tunnel syndrome: a prospective case series study.Quantitative imaging in medicine and surgery · 2026Article
- Contrast-enhanced magnetic resonance neurography aids in diagnosis and grading of carpal tunnel syndrome: a preliminary study.La Radiologia medica · 2026Article
- Association of Neighborhood Socioeconomic Status With Time to Consultation and Surgery for Carpal Tunnel Syndrome.Journal of hand surgery global online · 2026Article
- Associations between coeliac disease and musculoskeletal conditions: epidemiology and genetic evidence from a large-scale cohort study.Clinical rheumatology · 2026Article
- Ultrasonographic and Clinical Outcomes of Pulsed Ultrasound Versus Pulsed Shortwave Diathermy in Mild-to-Moderate Carpal Tunnel Syndrome: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- Tirzepatide Use Is Associated with Reduced Risk of Carpal Tunnel Syndrome in Overweight and Obese Adults.Clinical pharmacology and therapeutics · 2026Article
- Inflammation in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis of the Immune Profile.Journal of clinical medicine · 2026Review
- The Current Role of Physiotherapy in Systemic Light-Chain (AL) Amyloidosis and Multiple Myeloma.Life (Basel, Switzerland) · 2026Review
- Health-related factors and epigenetic alterations in metabolic comorbidities patients and smokers with carpal tunnel syndrome: a preliminary investigation of patient-derived samples.Journal of orthopaedic surgery and research · 2026Article
- Rate of Ipsilateral Carpal Tunnel Syndrome Increases After Shoulder Arthroplasty.Journal of hand surgery global online · 2026Article
- Carpal tunnel syndrome in systemic sclerosis: prevalence, clinical correlates, and diagnostic performance of ultrasound compared with nerve conduction studies.BMC rheumatology · 2026Article
- Surgical Versus Conservative Management for Carpal Tunnel Syndrome: An Updated Systematic Review of Randomised Trials.Brain sciences · 2026Review
- Wrist Flexor Spasticity and Hemiplegic-Contralateral Median Nerve Latency Asymmetry After Stroke: A Bilateral Nerve Conduction and Ultrasound Study.Diagnostics (Basel, Switzerland) · 2026Article
- Immune cells mediated the causal relationship between gut microbiota and carpal tunnel syndrome: A Mendelian randomization study.Medicine · 2026Article
- Prevalence and Risk of Carpal Tunnel Syndrome in Parkinson's Disease: A Systematic Review and Meta-Analysis.Journal of functional morphology and kinesiology · 2026Review
- Article
- Risk of new-onset glaucoma in people with carpal tunnel syndrome: a global-federated, multicenter retrospective cohort study.International journal of medical sciences · 2026Article
- Effectiveness and Safety of Ultrasound-Guided Pharmacopuncture for Carpal Tunnel Syndrome: Protocol for A Multicenter, Randomized, Assessor-Blinded, Waiting-List-Controlled Clinical Trial.Journal of pain research · 2026Article
- Risk of Psychiatric Disorders Following Carpal Tunnel Syndrome: A Nationwide Cohort Study.Psychiatry investigation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carpal tunnel syndrome (CTS) is the most common nerve entrapment disorder worldwide. The epidemiology and risk factors, including family burden, for developing CTS are multi-factorial. Despite much research, its intricate pathophysiological mechanism(s) are not fully understood. An underlying subclinical neuropathy may indicate an increased susceptibility to developing CTS. Although surgery is often performed for CTS, clear international guidelines to indicate when to perform non-surgical or surgical treatment, based on stage and severity of CTS, remain to be elucidated. Neurophysiological examination, using electrophysiology or ultrasonography, performed in certain circumstances, should correlate with the history and findings in clinical examination of the person with CTS. History and clinical examination are particularly relevant globally owing to lack of other equipment. Various instruments are used to assess CTS and treatment outcomes as well as the effect of the disorder on quality of life. The surgical treatment options of CTS - open or endoscopic - offer an effective solution to mitigate functional impairments and pain. However, there are risks of post-operative persistent or recurrent symptoms, requiring meticulous diagnostic re-evaluation before any additional surgery. Health-care professionals should have increased awareness about CTS and all its implications. Future considerations of CTS include use of linked national registries to understand risk factors, explore possible screening methods, and evaluate diagnosis and treatment with a broader perspective beyond surgery, including psychological well-being.
Indexed as
Identifiers
38782929What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.