SynthesisClinical child and family psychology review2024
A Systematic Review and Meta-Analysis of Impairment and Quality of Life in Children and Adolescents with Anxiety Disorders.
Synthesis in Clinical child and family psychology review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and narrative synthesis of evidence from randomised controlled trials: the impact of behaviour guidance techniques on dental anxiety in paediatric patients.BMC oral health · 2025Pooled it
- [Long-term courses of anxiety disorders].Der Nervenarzt · 2025Pooled it
- Using sleep to enhance exposure treatment for anxious children: A pilot study.The British journal of clinical psychology · 2026Trial
- Who engages? Machine learning insights into digital mindfulness-based intervention for generalized anxiety disorder.Journal of affective disorders · 2026Trial
- Trial
- Pilot Randomized Controlled Trial of the Emotion Detectives In-Out: A Blended Version of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children.Child psychiatry and human development · 2026Article
- Children's Internalizing Symptoms and Well-Being: The Role of Parental Anxiety and Health-Related Quality of Life.Pediatric reports · 2026Article
- Anxiety disorders: a cross-sectional study of clinical and biological associations.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Longitudinal Relationships Between Social Anxiety, Peer Victimisation, and Perceived Support Among Children.Behavioral sciences (Basel, Switzerland) · 2026Article
- The differential effects of psychotherapeutic and pharmacologic intervention on symptom severity and functioning in children and adolescents with internalizing problems: a systematic review protocol.Systematic reviews · 2026Article
- Italian Validation of the Brief Self-Reported Version of the Spence Children's Anxiety Scale for Children.Journal of clinical psychology · 2026Article
- Article
- Prevalence, outcomes, and effective interventions for anxiety disorders in children and adolescents.Discover mental health · 2026Article
- A novel deep learning model for objective quantification of generalized anxiety disorder severity using EEG functional connectivity.Frontiers in psychiatry · 2026Article
- Physical activity relates to adolescent social anxiety: evidence from a structural equation model involving resilience and self-efficacy.Frontiers in psychology · 2026Article
- Article
- Maternal Expectations and Overinvolvement, and Child Emotion Regulation in Children with and Without Anxiety Disorders: An Experimental Observational Study.International journal of environmental research and public health · 2025Observational
- Illness identity perception of adolescents with anxiety and mood disorders and its association with social functioning.Frontiers in public health · 2025Article
- Toward dimensional psychiatry in youth: A data-driven analysis of transdiagnostic internalizing symptoms in childhood and adolescence.PLOS mental health · 2025Article
- Measuring Anxiety and Depression in Adolescents: Psychometric Properties of the Overall Anxiety and Depression Severity and Impairment Scales.Clinical psychology & psychotherapyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety disorders are common, emerge during childhood, and pose a significant burden to society and individuals. Research evaluating the impact of anxiety on functional impairment and quality of life (QoL) is increasing; however, there is yet to be a systematic review and meta-analysis of these relationships in pediatric samples. This systematic review and meta-analysis were conducted to determine the extent of impairments in functioning and QoL that young people with anxiety disorders experience relative to their healthy peers, as well as sociodemographic and clinical moderators of these relationships. Studies were included when they compared young people (mean age range within studies 7-17 years) with a primary clinical anxiety disorder to a healthy comparison group and measured impairment and/or QoL via a validated instrument. A total of 12 studies met criteria for this review (N = 3,129 participants). A majority of studies (K = 9) assessed impairment as an outcome measure, and three assessed QoL outcomes. Meta-analysis of nine studies (N = 1,457 children) showed large relationships between clinical anxiety and life impairment (g = 3.23) with the strongest effects seen for clinician report (g = 5.00), followed by caregiver (g = 2.15) and child (g = 1.58) report. The small number of studies and diversity in methodology prevented quantitative investigation of moderating factors. In the systematic review of QoL outcomes, all three studies reported significantly poorer QoL for youth with anxiety disorders relative to unaffected peers. Findings support the importance of measuring functioning and QoL as outcomes in clinical research and practice among anxious young people.This study is registered with PROSPERO under the identification number CRD42023439040.
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