Evidence map›Paper›PMID 38782576›Full record

ArticleOccupational and environmental medicine2024

Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study.

Stephanie Mathieson, Alex Collie, Christopher G Maher, Christina Abdel Shaheed, Ting Xia, Stephen Gilbert, Giovanni E Ferreira, Michael F Di Donato

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Article in Occupational and environmental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie MathiesonSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia stephanie.mathieson@sydney.edu.au.ORCID 0000-0002-7335-8842
Alex CollieSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-2617-9339
Christopher G MaherSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-1628-7857
Christina Abdel ShaheedSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0003-1258-5125
Ting XiaMonash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-5033-6248
Stephen GilbertSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.
Giovanni E FerreiraSydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-8534-195X
Michael F Di DonatoSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-6531-5949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.

methodsWe analysed claim-level and service-level data from the Victorian workers' compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.

resultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.

conclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010-2017; and the time to first dispensing halved during this period.

Indexed as

AnalgesicsGabapentinLow Back PainWorkers' CompensationAdultDrug PrescriptionsFemaleHumansMaleMiddle AgedOccupational DiseasesRetrospective StudiesVictoriaAnalgesicsGabapentinBack PainHealth services researchVeterans

Identifiers

PMID38782576
PMCPMC11187357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.