Evidence map›Paper›PMID 38781502›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024

Five-year outcomes of different techniques for minimally invasive mitral valve repair in Barlow's disease.

Leo Pölzl, Can Gollmann-Tepeköylü, Felix Nägele, Kardelen Cetin, Johannes Spilka, Johannes Holfeld, Ulvi C Oezpeker, Luka Stastny, Michael Graber, Jakob Hirsch and 8 more

Erratum issuedAbstract read
In one paragraph

Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mitral Annular Disjunction: A Roadmap for the Surgeon.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
    Review
  7. Article
  8. [Transcatheter edge-to-edge repair using MitraClipZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Article
  9. Article
  10. Review
  11. Early Results of Minimally Invasive Mitral Valve Repair with Non-Resection Techniques in the Treatment of Barlow Disease.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Leo PölzlDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-6552-8899
Can Gollmann-TepeköylüDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Felix NägeleDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Kardelen CetinDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Johannes SpilkaDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Johannes HolfeldDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-6623-0595
Ulvi C OezpekerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Luka StastnyDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Michael GraberDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-2150-5473
Jakob HirschDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Clemens EnglerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-7808-1336
Julia DumfarthDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-1263-6909
Elfriede Ruttmann-UlmerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-5836-0875
Herbert HanglerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Michael GrimmDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Ludwig MüllerDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Daniel HöferDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Nikolaos BonarosDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-7656-5812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBarlow's disease is a specific sub-form of mitral valve (MV) disease, characterized by diffuse excessive tissue and multi segment prolapse. The anterolateral mini-thoracotomy represents the standard access for MV regurgitation in many centres. It still remains unclear which surgical technique provides the best results. Therefore, the aim of this study was to compare operative safety and mid-term outcomes after (i) isolated annuloplasty, (ii) use of additional artificial chordae or (iii) leaflet resection in patients suffering from Barlow's disease undergoing minimally invasive MV repair.

methodsA consecutive series of patients suffering from Barlow's disease undergoing minimally invasive MV surgery between 2001 and 2020 were analysed (n = 246). Patients were grouped and analysed according to the used surgical technique. The primary outcome was a modified Mitral Valve Academic Research Consortium combined end-point of mortality, reoperation due to repair failure or reoccurrence of severe mitral regurgitation within 5 years. The secondary outcome included operative success and safety up to 30 days.

resultsNo significant difference was found between the 3 surgical techniques with regard to operative safety (P = 0.774). The primary outcome did not differ between groups (P = 0.244). Operative success was achieved in 93.5% and was lowest in the isolated annuloplasty group (77.1%). Conversion to MV replacement was increased in patients undergoing isolated annuloplasty (P < 0.001).

conclusionsIsolated annuloplasty, use of additional artificial chordae and leaflet resection represent feasible techniques in Barlow patients undergoing minimally invasive MV surgery with comparable 5-year results. In view of the increased conversion rate in the annuloplasty group, the pathology should not be oversimplified.

Indexed as

Minimally Invasive Surgical ProceduresMitral ValveMitral Valve AnnuloplastyMitral Valve ProlapseAdultAgedFemaleHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedMitral Valve InsufficiencyRetrospective StudiesTreatment OutcomeBarlow’s diseaseCardiac surgeryMinimal invasive surgeryMitral valve regurgitation

Identifiers

PMID38781502
PMCPMC11150856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.