Evidence map›Paper›PMID 38780820›Full record

ArticleJournal of medical systems2024

Back to the Roots: Reconstructing Large and Complex Cranial Defects using an Image-based Statistical Shape Model.

Jianning Li, David G Ellis, Antonio Pepe, Christina Gsaxner, Michele R Aizenberg, Jens Kleesiek, Jan Egger

Abstract read
In one paragraph

Article in Journal of medical systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Probabilistic 3D Correspondence Prediction from Sparse Unsegmented Images.Machine learning in medical imaging. MLMI (Workshop) · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianning LiInstitute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital, Girardetstraße 2, 45131, Essen, Germany. Jianning.Li@uk-essen.de.
David G EllisDepartment of Neurosurgery, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Antonio PepeInstitute of Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16, Graz, 8010, Austria.
Christina GsaxnerInstitute of Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16, Graz, 8010, Austria.
Michele R AizenbergDepartment of Neurosurgery, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Jens KleesiekInstitute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital, Girardetstraße 2, 45131, Essen, Germany.
Jan EggerInstitute for Artificial Intelligence in Medicine (IKIM), Essen University Hospital, Girardetstraße 2, 45131, Essen, Germany. Jan.Egger@uk-essen.de.

Funding

Austrian Science Fund FWF KLI 1044Austrian Science Fund FWF KLI 678
6 · The paper itself

Abstract

Designing implants for large and complex cranial defects is a challenging task, even for professional designers. Current efforts on automating the design process focused mainly on convolutional neural networks (CNN), which have produced state-of-the-art results on reconstructing synthetic defects. However, existing CNN-based methods have been difficult to translate to clinical practice in cranioplasty, as their performance on large and complex cranial defects remains unsatisfactory. In this paper, we present a statistical shape model (SSM) built directly on the segmentation masks of the skulls represented as binary voxel occupancy grids and evaluate it on several cranial implant design datasets. Results show that, while CNN-based approaches outperform the SSM on synthetic defects, they are inferior to SSM when it comes to large, complex and real-world defects. Experienced neurosurgeons evaluate the implants generated by the SSM to be feasible for clinical use after minor manual corrections. Datasets and the SSM model are publicly available at https://github.com/Jianningli/ssm .

Indexed as

Neural Networks, ComputerSkullHumansImage Processing, Computer-AssistedModels, StatisticalPlastic Surgery ProceduresProstheses and ImplantsCranial implant designCraniectomyCranioplastyCraniotomyDeep learningDomain shiftGeneralizationStatistical shape model

Identifiers

PMID38780820
PMCPMC11116219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.