ArticleJournal of natural medicines2024
Daphnane diterpenoid orthoesters with an odd-numbered aliphatic side chain from Daphne pedunculata.
Article in Journal of natural medicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Liquid chromatography-mass spectrometry-based automated annotation program-assisted structural characterization of daphnane diterpenoids from Daphne genkwa.Journal of natural medicines · 2026Article
- Anti-HIV diterpenoids from Daphne pseudomezereum.Phytochemistry · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Daphnane diterpenoids were recognized for their extensive range of potent biological activities. In the present study, phytochemical investigation including LC-MS/MS analysis resulted in the identification of five daphnane diterpenoid orthoesters (1-5). Among the five daphnane diterpenoids, two previously unreported compounds, daphnepedunins I and J (2 and 4) were isolated from Daphne pedunculata. The structure of new compounds was elucidated with extensive physicochemical and spectroscopic analyses. Their structure was characterized by the presence of an unusual odd-numbered aliphatic chain connected to an orthoester. The isolated compounds were evaluated for their anti-HIV activity against HIV-1 infection of MT4 cells, and the results indicated that compound 1 showed the most potent anti-HIV activity with an IC
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