Body surface area is positively associated with ankle-brachial index.

Samuel Palmu, Hannu Kautiainen, Johan G Eriksson, Harri Hakovirta, Päivi E Korhonen

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Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Samuel PalmuDepartment of General Practice, University of Turku, Turku, Finland.ORCID 0009-0007-1463-3043

Hannu KautiainenFolkhälsan Research Center, Helsinki, Finland.

Johan G ErikssonFolkhälsan Research Center, Helsinki, Finland.

Harri HakovirtaDepartment of Surgery, University of Turku and Southwest Finland Wellbeing Services County, Turku, Finland.ORCID 0000-0002-1518-045X

Päivi E KorhonenDepartment of General Practice, University of Turku and Southwest Finland Wellbeing Services County, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnkle-brachial index (ABI) measurement is a widely used diagnostic test for lower extremity artery disease. Previously, a larger body surface area (BSA) has been associated with lower blood pressure and lower 2-h post-load glucose concentrations in the oral glucose tolerance test. Our aim was to evaluate whether BSA has an impact on ABI and the prevalence of lower ABI values.

methodsABI measurements were performed on 972 subjects aged 45 to 70 years at high cardiovascular disease (CVD) risk. Subjects with previously diagnosed kidney disease, CVD, and diabetes were excluded. Their BSA was calculated by the Mosteller formula. Study subjects were divided into ﬁve BSA levels corresponding to 12.5

resultsAfter adjustments for age, sex, pulse pressure, glucose regulation, waist circumference, alcohol intake, smoking status, leisure-time physical activity and medication, BSA level had a positive linear relationship with ABI (

conclusionBSA shows a positive linear relationship with ABI in CVD risk subjects without manifested CVD. The difference in ABI between men and women is modified by BSA and is appreciable when BSA is larger than 2.0 m

Indexed as

Ankle Brachial IndexBody Surface AreaAgedBlood PressureCardiovascular DiseasesFemaleHumansMaleMiddle AgedPeripheral Arterial DiseaseRisk FactorsAnkle-brachial index (ABI)body sizebody surface areaperipheral artery diseasesex differences

Identifiers

PMID38780467

DOI10.1177/00368504241251649

PMCPMC11119366

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.