Evidence map›Paper›PMID 38780442›Full record

ArticleHuman brain mapping2024

Longitudinal microstructural alterations surrounding subcortical ischemic stroke lesions detected by free-water imaging.

Felix L Nägele, Marvin Petersen, Carola Mayer, Marlene Bönstrup, Robert Schulz, Christian Gerloff, Götz Thomalla, Bastian Cheng

Abstract read
In one paragraph

Article in Human brain mapping, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felix L NägeleDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-3774-6765
Marvin PetersenDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0001-6426-7167
Carola MayerDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marlene BönstrupDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Robert SchulzDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christian GerloffDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Götz ThomallaDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bastian ChengDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-2434-1822

Funding

Deutsche Forschungsgemeinschaft 178316478 C2
6 · The paper itself

Abstract

In this study we explore the spatio-temporal trajectory and clinical relevance of microstructural white matter changes within and beyond subcortical stroke lesions detected by free-water imaging. Twenty-seven patients with subcortical infarct with mean age of 66.73 (SD 11.57) and median initial NIHSS score of 4 (IQR 3-7) received diffusion MRI 3-5 days, 1 month, 3 months, and 12 months after symptom-onset. Extracellular free-water and fractional anisotropy of the tissue (FA

Indexed as

Diffusion Magnetic Resonance ImagingIschemic StrokeWhite MatterAgedAnisotropyBrainFemaleHumansLongitudinal StudiesMaleMiddle AgedWaterWaterdiffusion MRIfree‐water imagingpenumbrasmall vessel diseasesubcortical stroke

Identifiers

PMID38780442
PMCPMC11114091

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.