Evidence map›Paper›PMID 38780074›Full record

ReviewHuman vaccines & immunotherapeutics2024

A worldwide overview for hexavalent vaccines and a glimpse into Turkiye's perspective.

Metehan Özen, Emin Ünüvar, Abdurrahman Yıldırım, Hakkı Akman, Süleyman Mevlitoğlu, Tamer Pehlivan

Abstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Infant protection from invasiveHuman vaccines & immunotherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Metehan ÖzenSchool of Medicine, Department of Pediatric Infectious Disease, Acıbadem University, İstanbul, Turkiye.ORCID 0000-0003-4088-3103
Emin ÜnüvarSchool of Medicine, Department of Pediatric Disease, Istanbul University, Istanbul, Turkiye.ORCID 0000-0003-2685-6483
Abdurrahman YıldırımPediatric Disease, Dr Abdurrahman Yıldırım Clinic, Istanbul, Turkiye.
Hakkı AkmanDepartment of Pediatric Disease, Güven Hospital, Ankara, Turkiye.
Süleyman MevlitoğluPediatric Disease, Dolunay Children Clinic, Antalya, Turkiye.
Tamer PehlivanPublic Health, Remedium Consulting Group, İzmir, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surge in recommended vaccinations for child's has spurred the development of combination vaccines, notably hexavalent vaccines, which provide multiple immunizations in a single dose. These vaccines offer various advantages, such as streamlining vaccination schedules, minimizing injection-related pain and exposure to preservatives, expanding vaccine coverage, and reducing administration costs. However, the intricate and expensive development of these vaccines presents substantial challenges, requiring increased investment and healthcare provider education to optimize their utilization and sustain high vaccination rates. Turkey, known for its robust vaccine coverage, strategic geographic location, and the influx of refugees, is at a critical juncture for integrating hexavalent vaccines into national programs. This transition is especially relevant given the rising vaccine hesitancy and the potential resurgence of vaccine-preventable diseases. This review assesses the deployment of hexavalent vaccines, examining their benefits and challenges through clinical trials and global experiences, with a specific emphasis on Turkiye's public health context.

Indexed as

Vaccine-Preventable DiseasesVaccines, CombinedHumansImmunization ProgramsImmunization ScheduleTurkeyVaccinationVaccination CoverageVaccination HesitancyVaccines, Combinedchildhood immunizationcombination vaccinesHexavalant vaccinesimmunogenicityvaccination strategiesvaccine safety

Identifiers

PMID38780074
PMCPMC11123514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.