Evidence map›Paper›PMID 38779643›Full record

ArticleAnnals of gastroenterology

Endoscopic ultrasound-guided portal pressure gradient measurement: a systematic review and meta-analysis.

Banreet Singh Dhindsa, Kyaw Min Tun, Alexandra Fiedler, Smit Deliwala, Syed Mohsin Saghir, Kyle Scholten, Daryl Ramai, Mohit Girotra, Saurabh Chandan, Amaninder Dhaliwal and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07703540 (Inferior Vena Cava Pressure as Alternative to Hepatic Venous Pressure for EUS-guided Portal Pressure Gradient Measurement), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07703540 completednot on this map

Inferior Vena Cava Pressure as Alternative to Hepatic Venous Pressure for EUS-guided Portal Pressure Gradient Measurement

TypeobservationalSponsorUniversity Hospital MuensterRan2026 to 2026Enrolled40ConditionsCirrhosis, Liver Disease Chronic, Portal HypertensionArmsHVP-PPG and IVCP-PPG
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Role of Endoscopic Ultrasound in Assessing Portal Hypertension: A State-of-the-Art Literature Review and Evolving Perspectives.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Pooled it
  3. Pooled it
  4. Review
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  6. Article
  7. Review
  8. Review
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  13. EUS-Guided Vascular Interventions: Recent Advances.Journal of clinical medicine · 2024
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Banreet Singh DhindsaDivision of Gastroenterology and Hepatology, Department of Medicine, New York University Grossman School of Medicine (Banreet Singh Dhindsa).
Kyaw Min TunDepartment of Internal Medicine, Kirk Kerkorian School of Medicine at UNLV, University of Nevada, Las Vegas, Nevada (Kyaw Min Tun).
Alexandra FiedlerDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, Nebraska (Alexandra Fiedler, Kyle Scholten, Ishfaq Bhat, Shailender Singh).
Smit DeliwalaDivision of Gastroenterology and Hepatology, Emory University School of Medicine, Atlanta, Georgia (Smit Deliwala).
Syed Mohsin SaghirDivision of Gastroenterology and Hepatology, Creighton University School of Medicine, Omaha, Nebraska (Syed Mohsin Saghir, Saurabh Chandan).
Kyle ScholtenDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, Nebraska (Alexandra Fiedler, Kyle Scholten, Ishfaq Bhat, Shailender Singh).
Daryl RamaiDivision of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah (Daryl Ramai).
Mohit GirotraDigestive Health Institute, Swedish Medical Center, Seattle, Washington (Mohit Girotra).
Saurabh ChandanDivision of Gastroenterology and Hepatology, Creighton University School of Medicine, Omaha, Nebraska (Syed Mohsin Saghir, Saurabh Chandan).
Amaninder DhaliwalMcLeod Health, Florence, South Carolina (Amaninder Dhaliwal).
Ishfaq BhatDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, Nebraska (Alexandra Fiedler, Kyle Scholten, Ishfaq Bhat, Shailender Singh).
Shailender SinghDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, Nebraska (Alexandra Fiedler, Kyle Scholten, Ishfaq Bhat, Shailender Singh).
Douglas G AdlerCenter for Advanced Therapeutic Endoscopy, Centura Health, Denver, CO (Douglas G. Adler), USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic ultrasound-guided portal pressure gradient measurement (EUS-PPG) is a new modality where the portal pressure is measured by directly introducing a needle into the hepatic vein and portal vein. This is the first systematic review and meta-analysis to evaluate the efficacy and safety of EUS-PPG. Methods: A comprehensive literature search was performed to identify pertinent studies. The primary outcomes assessed were the technical and clinical success of EUS-PPG. Technical success was defined as successful introduction of the needle into the desired vessel, while clinical success was defined as the correlation of the stage of fibrosis on the liver biopsy to EUS-PPG, or concordance of HVPG and EUS-PPG. The secondary outcomes were pooled rates for total and individual adverse events related to EUS-PPG. Pooled estimates were calculated using random-effects models with a 95% confidence interval (CI). Results: Eight cohort studies with a total of 178 patients were included in our analysis. The calculated pooled rates of technical success and clinical success were 94.6% (95%CI 88.5-97.6%; P=<0.001; Conclusions: EUS-PPG is a safe and effective modality for diagnosing portal hypertension. Further randomized controlled trials are needed to validate our findings.

Indexed as

cirrhosisEndoscopic ultrasoundportal hypertensionportal pressure gradient

Identifiers

PMID38779643
PMCPMC11107402

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.