ArticleWellcome open research2022
The PRECISE-DYAD protocol: linking maternal and infant health trajectories in sub-Saharan Africa.
Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed.
- PRECISE-DYAD: a prospective cohort study linking maternal and infant health trajectories in sub-Saharan Africa.BMJ open · 2026Observational
- Daily outdoor PMAtmospheric Environment: X · 2026Article
- An integrated climate-structured personal and ambient air pollution monitoring framework embedded within a pregnancy and postpartum cohort in Sub-Saharan Africa.Frontiers in global women's health · 2026Article
- Unequal exposure: spatio-temporal and structural determinants of personal PMFrontiers in global women's health · 2026Article
- Cohort Profile: PRECISE-DYAD: a prospective cohort study linking maternal and infant health trajectories in sub-Saharan Africa.medRxiv : the preprint server for health sciences · 2025Article
- Placental transfer of SARS-CoV-2 antibodies in mother-neonate pairs: a prospective nested cohort study.BMC infectious diseases · 2025Observational
- Article
- Community engagement approaches and lessons learned: a case study of the PRECISE pregnancy cohort study in Kenya.Frontiers in public health · 2025Article
- The PRECISE-DYAD Neurodevelopmental substudy protocol: neurodevelopmental risk in children of mothers with pregnancy complications.Wellcome open research · 2023Article
- The PRECISE-DYAD protocol: linking maternal and infant health trajectories in sub-Saharan Africa.Wellcome open research · 2022Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
Background: PRECISE-DYAD is an observational cohort study of mother-child dyads running in urban and rural communities in The Gambia and Kenya. The cohort is being followed for two years and includes uncomplicated pregnancies and those that suffered pregnancy hypertension, fetal growth restriction, preterm birth, and/or stillbirth. Methods: The PRECISE-DYAD study will follow up ~4200 women and their children recruited into the original PRECISE study. The study will add to the detailed pregnancy information and samples in PRECISE, collecting additional biological samples and clinical information on both the maternal and child health.Women will be asked about both their and their child's health, their diets as well as undertaking a basic cardiology assessment. Using a case-control approach, some mothers will be asked about their mental health, their experiences of care during labour in the healthcare facility. In a sub-group, data on financial expenditure during antenatal, intrapartum, and postnatal periods will also be collected. Child development will be assessed using a range of tools, including neurodevelopment assessments, and evaluating their home environment and quality of life. In the event developmental milestones are not met, additional assessments to assess vision and their risk of autism spectrum disorders will be conducted. Finally, a personal environmental exposure model for the full cohort will be created based on air and water quality data, combined with geographical, demographic, and behavioural variables. Conclusions: The PRECISE-DYAD study will provide a greater epidemiological and mechanistic understanding of health and disease pathways in two sub-Saharan African countries, following healthy and complicated pregnancies. We are seeking additional funding to maintain this cohort and to gain an understanding of the effects of pregnancies outcome on longer-term health trajectories in mothers and their children.
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