Evidence map›Paper›PMID 38779337›Full record

ArticleMolecular therapy. Methods & clinical development2024

Nanodysferlins support membrane repair and binding to TRIM72/MG53 but do not localize to t-tubules or stabilize Ca

Joaquin Muriel, Valeriy Lukyanenko, Thomas A Kwiatkowski, Yi Li, Sayak Bhattacharya, Kassidy K Banford, Daniel Garman, Hannah R Bulgart, Roger B Sutton, Noah Weisleder and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joaquin MurielDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Valeriy LukyanenkoDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Thomas A KwiatkowskiDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210, USA.
Yi LiDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Sayak BhattacharyaDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210, USA.
Kassidy K BanfordDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210, USA.
Daniel GarmanDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Hannah R BulgartDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210, USA.
Roger B SuttonDepartment of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Noah WeislederDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, OH 43210, USA.
Robert J BlochDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Funding

Interdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7M
Role of Dysferlin in T-Tubules of Skeletal MuscleR01AR064268 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI BLOCH, ROBERT J · 2014 to 2018
$1.9M
A Zeiss Duo Confocal Microscope for Shared Imaging FacilityS10RR024548 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANPIED, THOMAS A · 2008 to 2008
$500k
Cell Membrane Resealing in Inflammatory MyopathyR56AR078800 · NIAMS · OHIO STATE UNIVERSITY · PI JARJOUR, WAEL N, WEISLEDER, NOAH · 2022 to 2022
$284k
Advanced components for an existing spinning disk confocal in an established core imaging facilityS10OD026698 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANPIED, THOMAS A · 2019 to 2019
$274k
NCRR NIH HHS S10 RR024548NIAMS NIH HHS R01 AR064268NIAMS NIH HHS R56 AR078800NIAMS NIH HHS T32 AR007592NIH HHS S10 OD026698
6 · The paper itself

Abstract

Mutations in the

Indexed as

Ca2+ transientCa2+ wavesCICRDysferlinEC couplinginjurymembrane repairsarcolemmatransverse tubule

Identifiers

PMID38779337
PMCPMC11109471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.