Evidence map›Paper›PMID 38778803›Full record

ArticleResuscitation plus2024

Favorable resuscitation characteristics in patients undergoing extracorporeal cardiopulmonary resuscitation: A secondary analysis of the INCEPTION-trial.

Johannes F H Ubben, Samuel Heuts, Thijs S R Delnoij, Martje M Suverein, Renicus C Hermanides, Luuk C Otterspoor, Carlos V Elzo Kraemer, Alexander P J Vlaar, Joris J van der Heijden, Erik Scholten and 9 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Johannes F H UbbenDepartment of Anesthesiology and Pain Medicine, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands.
Samuel HeutsCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Thijs S R DelnoijDepartment of Intensive Care Medicine, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands.
Martje M SuvereinDepartment of Intensive Care Medicine, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands.
Renicus C HermanidesDepartment of Cardiology, Isala Clinics, Zwolle, the Netherlands.
Luuk C OtterspoorDepartment of Intensive Care Medicine, Catharina Hospital, Eindhoven, the Netherlands.
Carlos V Elzo KraemerDepartment of Intensive Care Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Alexander P J VlaarDepartment of Intensive Care Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Joris J van der HeijdenDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Erik ScholtenDepartment of Intensive Care Medicine, Sint Antonius Hospital, Nieuwegein, the Netherlands.
Corstiaan den UilDepartment of Intensive Care Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Dinis Dos Reis MirandaDepartment of Intensive Care Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Sakir AkinDepartment of Intensive Care Medicine, Haga Ziekehuis, The Hague, the Netherlands.
Jesse de MetzDepartment of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Iwan C C van der HorstCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Bjorn WinkensDepartment of Methodology and Statistics, Maastricht University, Maastricht, the Netherlands.
Jos G MaessenCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Roberto LorussoCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Marcel C G van de PollDepartment of Intensive Care Medicine, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used as a supportive treatment for refractory out-of-hospital cardiac arrest (OHCA). Still, there is a paucity of data evaluating favorable and unfavorable prognostic characteristics in patients considered for ECPR. Methods: We performed a previously unplanned post-hoc analysis of the multicenter randomized controlled INCEPTION-trial. The study group consisted of patients receiving ECPR, irrespective of initial group randomization. The patients were divided into favorable survivors (cerebral performance category [CPC] 1-2) and unfavorable or non-survivors (CPC 3-5). Results: In the initial INCEPTION-trial, 134 patients were randomized. ECPR treatment was started in 46 (66%) of 70 patients in the ECPR treatment arm and 3 (4%) of 74 patients in the conventional treatment arm. No statistically significant differences in baseline characteristics, medical history, or causes of arrest were observed between survivors ( Conclusion: The persistence of ventricular arrhythmia is a favorable prognostic factor in patients with refractory OHCA undergoing an ECPR-based treatment. Future studies are warranted to confirm this finding and to establish additional prognostic factors.

Indexed as

ECPROHCAPrognostic factorsRefractory ArrestResuscitationVentricular Arrhytmias

Identifiers

PMID38778803
PMCPMC11108965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.