Evidence map›Paper›PMID 38778802›Full record

ArticleResuscitation plus2024

Agonal breathing upon hospital arrival as a prognostic factor in patients experiencing out-of-hospital cardiac arrest.

Shinnosuke Kitano, Kensuke Suzuki, Chie Tanaka, Masamune Kuno, Nobuya Kitamura, Hideo Yasunaga, Shotaro Aso, Takashi Tagami

Registry-linked trialAbstract read
In one paragraph

Article in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07695766 (Evaluation of CPR Training and Agonal Breathing Recognition Among New Taipei City Police Officers in Out-of-Hospital Cardiac Arrest Events), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07695766 nacompletednot on this mapstarted 2026, after this paper: background citation

Evaluation of CPR Training and Agonal Breathing Recognition Among New Taipei City Police Officers in Out-of-Hospital Cardiac Arrest Events

TypeinterventionalSponsorFar Eastern Memorial HospitalRan2026 to 2026Enrolled3,439ConditionsOut-of-hospital Cardiac Arrest (OHCA), Agonal Breathing, Cardiopulmonary Resuscitation TrainingArmsCPR Refresher and Agonal Breathing Recognition Training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shinnosuke KitanoDepartment of Emergency and Critical Care Medicine, Nippon Medical School Tamanagayama Hospital, Japan.
Kensuke SuzukiDepartment of Emergency and Critical Care Medicine, Nippon Medical School Tamanagayama Hospital, Japan.
Chie TanakaDepartment of Emergency and Critical Care Medicine, Nippon Medical School Tamanagayama Hospital, Japan.
Masamune KunoDepartment of Emergency and Critical Care Medicine, Nippon Medical School Tamanagayama Hospital, Japan.
Nobuya KitamuraDepartment of Emergency and Critical Care Medicine, Kimitsu Chuo Hospital, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Japan.
Shotaro AsoDepartment of Real World Evidence, Graduate School of Medicine, The University of Tokyo, Japan.
Takashi TagamiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Agonal breathing is a relatively common symptom that follows cardiac arrest when the brainstem function is preserved. Agonal breathing is associated with favorable survival in patients experiencing out-of-hospital cardiac arrest (OHCA). While previous studies focused on agonal breathing observed in the pre-hospital setting for all study subjects, we focused on agonal breathing observed upon hospital arrival. In this multicenter prospective study, we aimed to assess the prognosis of patients exhibiting agonal breathing upon hospital arrival were compared. We hypothesized that agonal breathing at hospital arrival would be associated with favorable neurological outcomes among patients with OHCA. Methods: The data on incidence of agonal breathing were prospectively collected for all evaluable participants in a multicenter, observational study in Japan (SOS-KANTO [Survey of Survivors after Out-of-Hospital Cardiac Arrest in Kanto Area] 2017 Study). Groups with and without agonal breathing were compared upon hospital arrival. Propensity-score with inverse probability of treatment weighting (IPTW) analysis was performed to adjust for confounding factors. The primary outcome was a favorable neurological outcome (Cerebral Performance Category 1-2) at 1 month. Results: A total of 6,457 participants out of the 9,909 registered in SOS-KANTO 2017 (in which 42 facilities participated) were selected for the current study. There were 128 patients (2.0%) in the with-agonal breathing group and 6,329 (98.0%) in the withoutagonal breathing group. The primary outcome was 1.1% in the with-agonal breathing group and 0.6% in the without-agonal breathing group (risk difference, 0.55; 95% confidence interval, 0.23-0.87) after IPTW analysis. Conclusion: In this multicenter prospective study, agonal breathing at hospital arrival was significantly associated with better neurological outcomes and increased survival at 1 month. Thus, agonal breathing at hospital arrival may be a useful prognostic predictor for patients experiencing OHCA.

Indexed as

AgonalCardiac arrestCardiopulmonary resuscitation

Identifiers

PMID38778802
PMCPMC11109003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.