Evidence map›Paper›PMID 38778424›Full record

ArticleVeterinary research2024

Effect of oral administration of microcin Y on growth performance, intestinal barrier function and gut microbiota of chicks challenged with Salmonella Pullorum.

Wenjing Li, Zhiwei Zeng, Di Zhou, Guyao Wang, Zepeng Wang, Yu Li, Yu Han, Miaomiao Qin, Changqi Luo, Saixiang Feng and 1 more

Abstract read
In one paragraph

Article in Veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Frontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wenjing Li *College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zhiwei Zeng *College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Di ZhouCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Guyao WangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zepeng WangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yu LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yu HanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Miaomiao QinCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Changqi LuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Saixiang FengCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China. fengsx@scau.edu.cn.
Weisheng CaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China. caoscauvet@163.com.ORCID http://orcid.org/0000-0003-4546-7133

Funding

Agriculture Research System of China CARS-41Guangdong Province Enterprise Science and Technology Commissioner Project GDKTP2021017300National Key Research and Development Program of China 2022YFD1800904Technical System of Poultry Industry of Guangdong Province 2023KJ128
6 · The paper itself

Abstract

The lasso peptide microcin Y (MccY) effectively inhibits various serotypes of Salmonella in vitro, but the antibacterial effect against S. Pullorum in poultry is still unclear. This study was the first to evaluate the safety and anti-S. Pullorum infection of MccY in specific pathogen-free (SPF) chicks. The safety test showed that the body weight, IgA and IgM levels of serum, and cecal microbiota structure of 3 groups of chicks orally administrated with different doses of MccY (5 mg/kg, 10 mg/kg, 20 mg/kg) for 14 days were not significantly different from those of the control group. Then, the chicks were randomized into 3 groups for the experiment of anti-S. Pullorum infection: (I) negative control group (NC), (II) S. Pullorum-challenged group (SP, 5 × 10

Indexed as

BacteriocinsChickensGastrointestinal MicrobiomePoultry DiseasesSalmonella Infections, AnimalAdministration, OralAnimal FeedAnimalsAnti-Bacterial AgentsIntestinal Barrier FunctionRandom AllocationSalmonellaSpecific Pathogen-Free OrganismsAnti-Bacterial AgentsBacteriocinsmicrocingut microbiotaintestinal barrierMicrocin YSalmonella Pullorum

Identifiers

PMID38778424
PMCPMC11112776

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.