Evidence map›Paper›PMID 38778322›Full record

ArticleBMC oral health2024

The innovation of AI-based software in oral diseases: clinical-histopathological correlation diagnostic accuracy primary study.

Shaimaa O Zayed, Rawan Y M Abd-Rabou, Gomana M Abdelhameed, Youssef Abdelhamid, Khalid Khairy, Bassam A Abulnoor, Shereen Hafez Ibrahim, Heba Khaled

Abstract read
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Comparative diagnostic accuracy of ChatGPT models in salivary gland disease: a multimodal vignette-based evaluation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Artificial intelligence progress in the diagnosis of oral mucosal lesions: implications for pediatric dental health.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shaimaa O ZayedDepartment of Oral maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-6559-0609
Rawan Y M Abd-RabouFaculty of Oral Medicine & Dental Surgery, Misr University for Science and Technology, P. O. Box 77, Giza, Egypt.
Gomana M AbdelhameedGeneral Medicine, New Giza, Giza, Egypt.
Youssef AbdelhamidPhilosophy & Interactive Media Minors, New York University, Abu Dhabi, United Arab Emirates.
Khalid KhairyKafrel-Shiekh University, Kafrel-Shiekh, Egypt.
Bassam A AbulnoorFixes Prosthodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
Shereen Hafez IbrahimFaculty of Dentistry, Cairo University, Cairo, Egypt. Shereen.hafez@dentistry.cu.edu.eg.ORCID http://orcid.org/0000-0002-1047-124X
Heba KhaledLecturer of Oral Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0009-0005-5027-6069

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMachine learning (ML) through artificial intelligence (AI) could provide clinicians and oral pathologists to advance diagnostic problems in the field of potentially malignant lesions, oral cancer, periodontal diseases, salivary gland disease, oral infections, immune-mediated disease, and others. AI can detect micro-features beyond human eyes and provide solution in critical diagnostic cases.

objectiveThe objective of this study was developing a software with all needed feeding data to act as AI-based program to diagnose oral diseases. So our research question was: Can we develop a Computer-Aided Software for accurate diagnosis of oral diseases based on clinical and histopathological data inputs?

methodThe study sample included clinical images, patient symptoms, radiographic images, histopathological images and texts for the oral diseases of interest in the current study (premalignant lesions, oral cancer, salivary gland neoplasms, immune mediated oral mucosal lesions, oral reactive lesions) total oral diseases enrolled in this study was 28 diseases retrieved from the archives of oral maxillofacial pathology department. Total 11,200 texts and 3000 images (2800 images were used for training data to the program and 100 images were used as test data to the program and 100 cases for calculating accuracy, sensitivity& specificity).

resultsThe correct diagnosis rates for group 1 (software users), group 2 (microscopic users) and group 3 (hybrid) were 87%, 90.6, 95% respectively. The reliability for inter-observer value was done by calculating Cronbach's alpha and interclass correlation coefficient. The test revealed for group 1, 2 and 3 the following values respectively 0.934, 0.712 & 0.703. All groups showed acceptable reliability especially for Diagnosis Oral Diseases Software (DODS) that revealed higher reliability value than other groups. However, The accuracy, sensitivity & specificity of this software was lower than those of oral pathologists (master's degree).

conclusionThe correct diagnosis rate of DODS was comparable to oral pathologists using standard microscopic examination. The DODS program could be utilized as diagnostic guidance tool with high reliability & accuracy.

Indexed as

Artificial IntelligenceMouth DiseasesSoftwareDiagnosis, Computer-AssistedHumansMachine LearningMouth NeoplasmsSensitivity and SpecificityArtificial intelligenceDeep learningOral diseases

Identifiers

PMID38778322
PMCPMC11112957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.