Evidence map›Paper›PMID 38778303›Full record

Observational studyBMC palliative care2024

Patterns of care at the end of life: a retrospective study of Italian patients with advanced breast cancer.

Irene Giannubilo, Linda Battistuzzi, Eva Blondeaux, Tommaso Ruelle, Francesca Benedetta Poggio, Giulia Buzzatti, Alessia D'Alonzo, Federica Della Rovere, Maria Maddalena Latocca, Chiara Molinelli and 9 more

Abstract readObservational Study
In one paragraph

Observational study in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Irene GiannubiloU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy. irenegiannubilo@gmail.com.
Linda BattistuzziU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Eva BlondeauxU.O. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genova, IT, Italy.
Tommaso RuelleU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Francesca Benedetta PoggioU.O.C. Clinica Di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Giulia BuzzattiU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Alessia D'AlonzoU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Federica Della RovereSSD Cure Palliative Ed Hospice, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Maria Maddalena LatoccaU.O.C. Clinica Di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Chiara MolinelliU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Maria Grazia RazetiDepartment of Internal Medicine and Medical Sciences (DiMI), School of Medicine, University of Genova, Genova, Italy.
Simone NardinU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Luca AreccoDepartment of Internal Medicine and Medical Sciences (DiMI), School of Medicine, University of Genova, Genova, Italy.
Marta PerachinoDepartment of Internal Medicine and Medical Sciences (DiMI), School of Medicine, University of Genova, Genova, Italy.
Diletta FaveroU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Roberto BoreaU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Paolo PronzatoU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Lucia Del MastroDepartment of Internal Medicine and Medical Sciences (DiMI), School of Medicine, University of Genova, Genova, Italy.
Claudia BighinU.O. Oncologia Medica 2, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo better understand the type of care offered to Italian patients with advanced breast cancer at the End-of-Life (EoL), we conducted a retrospective observational study. EoL was defined as the period of six months before death.

methodsOne hundred and twenty-one patients with advanced breast cancer (ABC) treated at IRCCS San Martino Policlinic Hospital who died between 2017 and 2021 were included. Data about patient, disease, and treatment characteristics from breast cancer diagnosis to death, along with information about comorbidities, medications, imaging, specialist evaluations, hospitalization, palliative care and home care, hospice admissions, and site of death were collected.

results98.3% of the patients received at least one line of active treatment at EoL; 52.8% were hospitalized during the selected period. Palliative (13.9%), psychological (7.4%), and nutritional evaluations (8.2%) were underutilized. Palliative home care was provided to 52% of the patients. Most of the patients died at home (66.1%) and fewer than one out of five (18.2%) died at the hospital. Among the patients who died at home, 27.3% had no palliative support.

conclusionsOur findings indicate that palliative care in EoL breast cancer patients is still inadequate. Only a minority of patients had psychological and nutritional support While low nutritional support may be explained by the fact that typical symptoms of ABC do not involve the gastrointestinal tract, the lack of psychological support suggests that significant barriers still exist. Data on the site of death are encouraging, indicating that EoL management is increasingly home centered in Italy.

Indexed as

Breast NeoplasmsPalliative CareTerminal CareAdultAgedAged, 80 and overFemaleHome Care ServicesHumansItalyMiddle AgedRetrospective StudiesBreast cancerEnd of lifePalliative care

Identifiers

PMID38778303
PMCPMC11110270

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.