ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024
The prognostic value of immune-nutritional status in metastatic colorectal cancer: Prognostic Nutritional Index (PNI).
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Predictors of Metastatic Lymph Node Burden in Colorectal Cancer: A Negative Binomial Regression Analysis.Life (Basel, Switzerland) · 2026Article
- Comparative Prognostic Performance of Nutritional, Immuneinflammatory, and Anthropometric Indices for Cardiovascular and All-cause Mortality in Older Adults with Cardiovascular Disease (NHANES 2009-2018).Annals of geriatric medicine and research · 2026Article
- Preoperative Immunonutritional Indices in Colorectal Cancer: The Contribution of Albumin, Time-Dependence of Effect, and Threshold Transportability in a Saudi Cohort.Current oncology (Toronto, Ont.) · 2026Article
- Assessment of Muscle Function Decline and Cachexia-Related Biomarkers in Hospitalized Oncology Patients: Study Protocol.Biomedicines · 2026Article
- Association of the global inflammatory-nutritional index (GINI) with time to next treatment and overall survival in patients with metastatic colorectal cancer receiving third-line therapy: a real-world retrospective study.Journal of gastrointestinal oncology · 2026Article
- Systemic Inflammatory Biomarkers as Prognostic Indicators in Metastatic Colorectal Cancer: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2026Observational
- The interplay between tumor-intrinsic KRT6A and host-derived immune-nutritional status (PNI) defines prognosis in resectable PDAC.Scientific reports · 2026Article
- Comparative Prognostic Accuracy of Objective Nutritional Indices in Critically Ill Patients with Sepsis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Longitudinal trajectories of nutritional markers in patients with de novo Stage IV gastric cancer: a descriptive analysis using one-year survival as a reference.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Diagnostic utility and discriminative ability of cholesterol-modified prognostic nutritional index and inflammatory indicators in colorectal cancer: a retrospective case-control study.Scientific reports · 2026Article
- Prognostic Value of Albumin-to-CEA Ratio in Metastatic Colorectal Cancer: A Retrospective Study.Biomedicines · 2026Article
- Prognostic Value of HALP and PNI Scores in Predicting 6-Month Mortality Among Geriatric Hip Fracture Patients.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- The prognostic nutritional index improves risk stratification for acute pulmonary embolism.iScience · 2026Article
- Coordinated dynamics of circulating neutrophils, regulatory T lymphocytes, myeloid derived suppressor cells and distinct granulocytic subsets reveal a complex immune network in metastatic colorectal cancer.Frontiers in oncology · 2026Article
- Article
- A Novel Prognostic Model Based on Prognostic Nutritional Index and Systemic Immune-Inflammation Index for Cancer Patients Treated with Immune Checkpoint Inhibitors.Cancer management and research · 2026Article
- Immunologically-based nutritional status assessment amongst preoperative colorectal cancer patients - does it link to TNM stage.Frontiers in immunology · 2026Article
- Clinical phenotype identification based on inflammation-nutrition-coagulation biomarkers in advanced non-small cell lung cancer.Frontiers in nutrition · 2026Article
- Prognostic nutritional index at discharge as a practical bedside tool for long-term all-cause mortality risk in pneumonia-induced sepsis survivors.Frontiers in nutrition · 2026Article
- Pretreatment prognostic nutritional index and immune status for response to preoperative neoadjuvant chemotherapy in cervical squamous cell carcinoma: an exploratory retrospective study.Frontiers in oncology · 2026Article
Corrections and comments
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4 authors.
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Abstract
backround and purposeA low Prognostic Nutritional Index (PNI) value, which reflects immune nutrition and inflammation around the tumor, is associated with an unfavorable prognosis, and it was aimed to reveal its prognostic value in metastatic colorectal cancer (CRC).
methodsIn our retrospective cross-sectional study, patients with a diagnosis of metastatic colorectal disease without active infection, between January 2010 and December 2016 were included. The PNI values at the time of diagnosis were calculated according to the formula (10 × serum albumin (g/dL)) + (0.005 × total lymphocyte value).
resultsThe mean PNI value of 253 patients included in the study was 46.6. While 53.75% (n = 136) of the patients had a PNI value of 46.6 and above, 46.25% (n = 117) had a PNI value below 46.6. The overall survival (OS) of the group with a PNI of 46.6 and above was statistically significantly longer (53.06 months vs 38.80 months, p = 0.039). The PFS duration of the group with PNI below 46.6 was 25.66 months, while the PFS duration of the group with PNI above 46.6 was not reached (p = 0.265).
conclusionPNI is a simple and inexpensive index that evaluates the immunonutritional status, and it is a prognostic marker that can be easily used in patients with metastatic colorectal cancer as in other cancer types.
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