Evidence map›Paper›PMID 38776918›Full record

ArticleImmunity2024

The CD8

Willem Van Der Byl, Simone Nüssing, Timothy J Peters, Antonio Ahn, Hanjie Li, Guy Ledergor, Eyal David, Andrew S Koh, Mayura V Wagle, Christian Deo T Deguit and 18 more

Abstract read
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. CD8Nature reviews. Cardiology · 2026
    Review
  4. CD8 T Cell Sensing of Type I Interferon Impacts Anergy.European journal of immunology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The diversity of CD8Nature reviews. Immunology · 2025
    Review
  10. A Dapl1Science advances · 2025
    Article
  11. PD-1 expressing islet-specific CD4Immunology and cell biology · 2025
    Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

  • Commented on by
    CD82024
5 · Who and what money

Authors and funding

28 authors.

Willem Van Der BylThe Kirby Institute for Infection and Immunity, UNSW, Sydney, NSW, Australia; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW, Australia.
Simone NüssingCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Timothy J PetersGarvan Institute of Medical Research, Sydney, NSW, Australia; University of New South Wales Sydney, Sydney, NSW, Australia.
Antonio AhnCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Hanjie LiDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Guy LedergorDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Eyal DavidDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Andrew S KohDepartment of Pathology, University of Chicago, Chicago, IL, USA.
Mayura V WagleGarvan Institute of Medical Research, Sydney, NSW, Australia; John Curtin School of Medical Research, ANU, Canberra, ACT, Australia.
Christian Deo T DeguitCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Maria N de MenezesCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Avraham TraversCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Shienny SampurnoCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Kelly M RamsbottomCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Rui LiCenter for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.
Axel KalliesThe Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne, Melbourne, VIC, Australia.
Paul A BeavisCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Ralf JungmannFaculty of Physics and Center for Nanoscience, Ludwig Maximilian University, Munich, Germany; Max Planck Institute of Biochemistry, Martinsried, Germany.
Maartje M C BastingsInstitute of Materials, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; Interfaculty Bioengineering Institute, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Gabrielle T BelzThe Frazer Institute, The University of Queensland, Brisbane, QLD, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Shom GoelCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Joseph A TrapaniCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Gerald R CrabtreeCenter for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA; Departments of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA.
Howard Y ChangCenter for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.
Ido AmitDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Chris C GoodnowSchool of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW, Australia; Garvan Institute of Medical Research, Sydney, NSW, Australia.
Fabio LucianiThe Kirby Institute for Infection and Immunity, UNSW, Sydney, NSW, Australia; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW, Australia. Electronic address: luciani@unsw.edu.au.
Ian A ParishCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; John Curtin School of Medical Research, ANU, Canberra, ACT, Australia. Electronic address: ian.parish@petermac.org.

Funding

ATP-Dependent Chromatin Remodeling in Human MalignancyR01CA163915 · NCI · STANFORD UNIVERSITY · PI Gerald R. Crabtree · 2012 to 2026
$5.4M
HIJACKING CANCER DRIVERS TO ACTIVATE PROAPOPTOTIC GENES IN DLBCLR01CA276167 · NCI · STANFORD UNIVERSITY · PI Gerald R. Crabtree, NATHANAEL Schiander GRAY · 2023 to 2026
$2.2M
NCI NIH HHS R01 CA163915NCI NIH HHS R01 CA276167
6 · The paper itself

Abstract

Peripheral CD8

Indexed as

CD8-Positive T-LymphocytesCell DifferentiationImmune ToleranceProtein BiosynthesisReceptors, Antigen, T-CellAnimalsAutoantigensMiceMice, Inbred C57BLSignal TransductionAutoantigensReceptors, Antigen, T-CellautoimmunitycancerCD8(+) T celldifferentiationdysfunctioneffector T cellexhaustionimmunotherapystem-like T celltolerance

Identifiers

PMID38776918
PMCPMC11807353

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.