Evidence map›Paper›PMID 38776539›Full record

ArticleJMIR formative research2024

Using a Semiautomated Procedure (CleanADHdata.R Script) to Clean Electronic Adherence Monitoring Data: Tutorial.

Carole Bandiera, Jérôme Pasquier, Isabella Locatelli, Marie P Schneider

Abstract read
In one paragraph

Article in JMIR formative research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Carole Bandiera *School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-9996-3100
Jérôme Pasquier *Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-5554-2988
Isabella LocatelliCenter for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-0870-1461
Marie P SchneiderSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-7557-9278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient adherence to medications can be assessed using interactive digital health technologies such as electronic monitors (EMs). Changes in treatment regimens and deviations from EM use over time must be characterized to establish the actual level of medication adherence.

objectiveWe developed the computer script CleanADHdata.R to clean raw EM adherence data, and this tutorial is a guide for users.

methodsIn addition to raw EM data, we collected adherence start and stop monitoring dates and identified the prescribed regimens, the expected number of EM openings per day based on the prescribed regimen, EM use deviations, and patients' demographic data. The script formats the data longitudinally and calculates each day's medication implementation.

resultsWe provided a simulated data set for 10 patients, for which 15 EMs were used over a median period of 187 (IQR 135-342) days. The median patient implementation before and after EM raw data cleaning was 83.3% (IQR 71.5%-93.9%) and 97.3% (IQR 95.8%-97.6%), respectively (Δ+14%). This difference is substantial enough to consider EM data cleaning to be capable of avoiding data misinterpretation and providing a cleaned data set for the adherence analysis in terms of implementation and persistence.

conclusionsThe CleanADHdata.R script is a semiautomated procedure that increases standardization and reproducibility. This script has broader applicability within the realm of digital health, as it can be used to clean adherence data collected with diverse digital technologies.

Indexed as

algorithmscodecodingcomputer programmingcomputer sciencecomputer scriptdata cleaningdata managementdigital pharmacydigital technologyelectronic adherence monitoringmedication adherencemedicationsRresearch methodologysemiautomated

Identifiers

PMID38776539
PMCPMC11153970

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