Evidence map›Paper›PMID 38776461›Full record

ArticleACS chemical neuroscience2024

Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [

Yanyan Kong, Lei Cao, Jiao Wang, Junyi Zhuang, Yongshan Liu, Lei Bi, Yifan Qiu, Yuyi Hou, Qi Huang, Fang Xie and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yanyan KongPET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Lei CaoPET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Jiao WangLab of Molecular Neural Biology, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Junyi ZhuangLab of Molecular Neural Biology, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Yongshan LiuGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China.
Lei BiGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China.
Yifan QiuGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China.
Yuyi HouGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China.
Qi HuangPET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Fang XiePET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Yunhao YangPET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Kuangyu ShiDepartment of Nuclear Medicine, University Hospital, Inselspital Bern, Bern 3010, Switzerland.
Axel RomingerDepartment of Nuclear Medicine, University Hospital, Inselspital Bern, Bern 3010, Switzerland.
Yihui GuanPET Center, Huashan Hospital, Fudan University, Shanghai 200235, China.
Hongjun JinGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China.ORCID 0000-0002-1522-1098
Ruiqing NiInstitute for Regenerative Medicine, University of Zurich, Zurich 8952, Switzerland.ORCID 0000-0002-0793-2113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation plays an important role in Alzheimer's disease and primary tauopathies. The aim of the current study was to map [

Indexed as

Positron-Emission TomographyReceptors, Purinergic P2X7TauopathiesAlzheimer DiseaseAnimalsBrainDisease Models, AnimalFluorine RadioisotopesMiceMice, Transgenictau ProteinsFluorine RadioisotopesReceptors, Purinergic P2X7tau ProteinsAlzheimer’s diseaseamyloid-βgliaP2X7RPETtau

Identifiers

PMID38776461
PMCPMC11157487

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.