Evidence map›Paper›PMID 38776250›Full record

ArticleACS applied bio materials2024

Materials Characterization of Stereolithography 3D Printed Polymer to Develop a Self-Driven Microfluidic Device for Bioanalytical Applications.

Britanny L Stark, Michelle Gamboa, Aibhlin Esparza, Truman J Cavendar-Word, Diego Bermudez, Luisa Carlon, David A Roberson, Binata Joddar, Sylvia Natividad-Diaz

Abstract read
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. SLA-Printed BaTiOACS omega · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Britanny L StarkDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Michelle GamboaDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Aibhlin EsparzaDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Truman J Cavendar-WordDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Diego BermudezDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Luisa CarlonDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
David A RobersonDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.
Binata JoddarDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.ORCID 0000-0002-9157-3140
Sylvia Natividad-DiazDepartment of Metallurgical, Materials, and Biomedical Engineering (MMBME), The University of Texas at El Paso (UTEP), 500 West University Avenue, El Paso, Texas 79968, United States.ORCID 0000-0002-1928-829X

Funding

UTEP Border Biomedical Research CenterU54MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI Gabriel Andrew Frietze · 2019 to 2026
$35.1M
3D in vitro Human Stem Cell-derived Cardiovascular Tissue Model and Microfluidic Platform for Targeted Preclinical Drug ScreeningSC2GM144164 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI NATIVIDAD-DIAZ, SYLVIA · 2022 to 2024
$455k
NIGMS NIH HHS SC2 GM144164NIMHD NIH HHS U54 MD007592
6 · The paper itself

Abstract

Stereolithography (SLA) 3D printing is a rapid prototyping technique and reproducible manufacturing platform, which makes it a useful tool to develop advanced microfluidic devices for bioanalytical applications. However, limited information exists regarding the physical, chemical, and biological properties of the photocured polymers printed with SLA. This study demonstrates the characterization of a commercially available SLA 3D printed polymer to evaluate the potential presence of any time-dependent changes in material properties that may affect its ability to produce functional, capillary-action microfluidic devices. The printed polymer was analyzed with Fourier transform infrared-attenuated total reflectance, contact angle measurements, tensile test, impact test, scanning electron microscopy, and fluid flow analysis. Polymer biocompatibility was assessed with propidium iodide flow cytometry and an MTT assay for cell viability. The material characterization and biocompatibility results were then implemented to design and fabricate a self-driven capillary action microfluidic device for future use as a bioanalytical assay. This study demonstrates temporally stable mechanical properties and biocompatibility of the SLA polymer. However, surface characterization through contact angle measurements shows the polymer's wettability changes over time which indicates there is a limited postprinting period when the polymer can be used for capillary-based fluid flow. Overall, this study demonstrates the feasibility of implementing SLA as a high-throughput manufacturing method for capillary action microfluidic devices.

Indexed as

Biocompatible MaterialsPolymersPrinting, Three-DimensionalCell SurvivalHumansLab-On-A-Chip DevicesMaterials TestingMicrofluidic Analytical TechniquesParticle SizeStereolithographyBiocompatible MaterialsPolymers3D printingcapillary flowmaterials characterizationmicrofluidicsstereolithography

Identifiers

PMID38776250
PMCPMC11653401

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.