Evidence map›Paper›PMID 38776142›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024

Impact of coronary calcium morphology on intravascular lithotripsy.

Angela McInerney, Alejandro Travieso, Adrián Jerónimo Baza, Fernando Alfonso, David Del Val, Enrico Cerrato, Juan Garcia de Lara, Eduardo Pinar, Armando Perez de Prado, Pilar Jimenez Quevedo and 16 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06736665 (Comparative Efficacy of Orbital Atherectomy and Intravascular Lithotripsy in the Treatment of Calcified Coronary Nodules. The ORBIT-SHOCK Pilot Study.), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06736665 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparative Efficacy of Orbital Atherectomy and Intravascular Lithotripsy in the Treatment of Calcified Coronary Nodules. The ORBIT-SHOCK Pilot Study.

TypeinterventionalSponsorSpanish Society of CardiologyRan2025 to 2027Enrolled50ConditionsCoronary Arterial Disease (CAD), Coronary Calcification, Coronary Calcified Nodules, Orbital AtherectomyArmsOrbital atherectomy, Intravascular lithotripsy, Optical Coherence Tomography (OCT), Percutaneous coronary intervention with stent implantation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Long-term predictors of target vessel failure after intracoronary lithotripsy: 12-month results from the France LILI registry.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  6. Article
  7. Percutaneous coronary intervention for calcified and resistant lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Angela McInerneyDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Alejandro TraviesoDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Adrián Jerónimo BazaDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Fernando AlfonsoDepartment of Cardiology, Hospital Universitario La Princesa, IIS-IP, CIBER-CV, Madrid, Spain.
David Del ValDepartment of Cardiology, Hospital Universitario La Princesa, IIS-IP, CIBER-CV, Madrid, Spain.
Enrico CerratoInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Italy.
Juan Garcia de LaraDepartment of Cardiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spai.
Eduardo PinarDepartment of Cardiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spai.
Armando Perez de PradoDepartment of Cardiology, Hospital Universitario de León, León, Spain.
Pilar Jimenez QuevedoDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Gabriela Tirado-ConteDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Luis Nombela-FrancoDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Salvatore BrugalettaCardiology Department, Hospital Clínic Cardiovascular Institute, Hospital Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Pedro Cepas-GuillénCardiology Department, Hospital Clínic Cardiovascular Institute, Hospital Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Manel SabatéCardiology Department, Hospital Clínic Cardiovascular Institute, Hospital Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Héctor Cubero GallegoDepartamento de Cardiología Intervencionista, Hospital del Mar, IMIM, Universidad Autónoma, Barcelona, Spain.
Beatriz VaquerizoDepartamento de Cardiología Intervencionista, Hospital del Mar, IMIM, Universidad Autónoma, Barcelona, Spain.
Alfonso JuradoDepartamento de Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario la Paz, Madrid, Spain.
Ferdinando VarbellaInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Italy.
Marcelo JimenezCardiac Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain.
Artemio Garcia EscobarDepartamento de Cardiología Intervencionista, Servicio de Cardiología, Hospital Universitario la Paz, Madrid, Spain.
José Maria de la TorreHospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain.
Ignacio Amat SantosCIBERCV, Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Victor Alfonso Jimenez DiazInterventional Cardiology, Hospital Álvaro Cunqueiro, Vigo, Spain.
Javier EscanedDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.
Nieves GonzaloDepartment of Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Universidad Complutense de Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary calcification negatively impacts optimal stenting. Intravascular lithotripsy (IVL) is a new calcium modification technique.

aimsWe aimed to assess the impact of different calcium morphologies on IVL efficacy.

methodsThis was a prospective, multicentre study (13 tertiary referral centres). Optical coherence tomography (OCT) was performed before and after IVL, and after stenting. OCT-defined calcium morphologies were concentric (mean calcium arc >180°) and eccentric (mean calcium arc ≤180°). The primary outcomes were angiographic success (residual stenosis <20%) and the presence of fracture by OCT in concentric versus eccentric lesions.

resultsNinety patients were included with a total of 95 lesions: 47 concentric and 48 eccentric. The median number of pulses was 60 (p=1.00). Following IVL, the presence of fracture was not statistically different between groups (79.0% vs 66.0% for concentric vs eccentric; p=0.165). The number of fractures/lesion (4.2±4.4 vs 2.3±2.8; p=0.018) and ≥3 fractures/lesion (57.1% vs 34.0%; p=0.029) were more common in concentric lesions. Angiographic success was numerically but not statistically higher in the concentric group (87.0% vs 76.6%; p=0.196). By OCT, no differences were noted in final minimum lumen area (5.9±2.2 mm

conclusionsIn this prospective, multicentre study, the effectiveness of IVL followed by stenting was not significantly affected by coronary calcium morphology.

Indexed as

Coronary AngiographyCoronary Artery DiseaseLithotripsyTomography, Optical CoherenceVascular CalcificationAgedCalciumCoronary VesselsFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionProspective StudiesStentsTreatment OutcomeCalcium

Identifiers

PMID38776142
PMCPMC11100505

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.