Evidence map›Paper›PMID 38776048›Full record

ReviewJournal of cardiovascular translational research2024

Exosome is a Fancy Mobile Sower of Ferroptosis.

Qin Hou, Siyu Ouyang, Zhongcheng Xie, Yinling He, Yunong Deng, Jiamin Guo, Panpan Yu, Xiaoqian Tan, Wentao Ma, Pin Li and 10 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Qin Hou *Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.ORCID http://orcid.org/0000-0003-4523-6036
Siyu Ouyang *Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Zhongcheng Xie *Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Yinling HeHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Yunong DengHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Jiamin GuoHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Panpan YuHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Xiaoqian TanHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Wentao MaHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Pin LiHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Jiang YuClass of Clinical Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Qinger MoClass of Clinical Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Zhixia ZhangClass of Clinical Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Dandan ChenClass of Clinical Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Xiaoyan LinHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Zhiyang LiuHengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Xi ChenClinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.
Tianhong PengClinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. thpeng67@163.com.
Liang LiDepartment of Physiology, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. 26002860@qq.com.
Wei XieClinical Anatomy & Reproductive Medicine Application Institute, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. weixiehy@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, nano-sized small extracellular vesicles, have been shown to serve as mediators between intercellular communications by transferring bioactive molecules, such as non-coding RNA, proteins, and lipids from secretory to recipient cells, modulating a variety of physiological and pathophysiological processes. Recent studies have gradually demonstrated that altered exosome charges may represent a key mechanism driving the pathological process of ferroptosis. This review summarizes the potential mechanisms and signal pathways relevant to ferroptosis and then discusses the roles of exosome in ferroptosis. As well as transporting iron, exosomes may also indirectly convey factors related to ferroptosis. Furthermore, ferroptosis may be transmitted to adjacent cells through exosomes, resulting in cascading effects. It is expected that further research on exosomes will be conducted to explore their potential in ferroptosis and will lead to the creation of new therapeutic avenues for clinical diseases.

Indexed as

ExosomesFerroptosisIronSignal TransductionAnimalsHumansIronExosomeFerroptosisLipid peroxidationMicroRNAsOxidative stress

Identifiers

PMID38776048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.