ArticleInternal and emergency medicine2024
Prognostic role of serum albumin levels in patients with chronic heart failure.
Article in Internal and emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Albumin Levels and the Risk of Heart Failure in Patients Undergoing Coronary Angiography for Different Indications.Journal of clinical medicine · 2026Article
- Reply to Yavuz, S. Comment on "Martire et al. Prognostic Role of High-Sensitivity C-Reactive Protein/Albumin Ratio in Heart Failure Patients.Biomedicines · 2026Article
- Correlation analysis of Serum NT-pro-BNP, IGFBP-7 and CTRP12 levels in chronic heart failure patients.Journal of medical biochemistry · 2026Article
- Association between lactate-to-albumin ratio and 28-day mortality in critically ill patients with HFpEF: a retrospectively cohort study.Scientific reports · 2026Article
- Global trends and projections in cardiovascular disease-related heart failure, 1990-2050: an analysis of the Global Burden of Disease 2021 data.Internal and emergency medicine · 2026Article
- Prognostic Role of High-Sensitivity C-Reactive Protein/Albumin Ratio in Heart Failure Patients.Biomedicines · 2026Article
- Association Between Mitral Annular Calcification and Ventricular Tachycardia in Patients with Reduced and Mildly Reduced Ejection Fraction.Journal of clinical medicine · 2026Article
- Associations Between Controlling Nutritional Status and Allostatic Load With Heart Failure Across Different Depressive States: A Cross-Sectional Study Using NHANES 2005-2018 Data.Reviews in cardiovascular medicine · 2026Article
- Analysis of the value of nutritional status indexes (ALB, Hb, GNRI) in prognostic assessment of elderly patients with chronic heart failure.Frontiers in cardiovascular medicine · 2026Article
- Uric acid-to-albumin ratio × monocyte-to-lymphocyte ratio is a novel biomarker for predicting all-cause mortality and cardiovascular mortality in patients with ST-segment elevation myocardial infarction.Coronary artery disease · 2025Article
- Prognostic role of sarcopenia in heart failure patients.Cardiovascular diabetology · 2025Article
- Prognostic Value of the NT-proBNP-to-Albumin Ratio (NTAR) for In-Hospital Mortality in Chronic Heart Failure Patients.Biomedicines · 2025Article
- Comparing Inflammatory Biomarkers in Cardiovascular Disease: Insights from the LURIC Study.International journal of molecular sciences · 2025Article
- Lactate dehydrogenase to albumin ratio and prognosis in patients with acute exacerbation of chronic obstructive pulmonary disease: a retrospective cohort study.BMC pulmonary medicine · 2025Article
- Letter to the editor to ''Prognostic role of serum albumin levels in patients with chronic heart failure''.Internal and emergency medicine · 2025Article
- Lower albumin levels are associated with 1-year mortality in older patients hospitalized for acute heart failure: THE ALBIMED-HF study.Internal and emergency medicine · 2025Article
- Systemic inflammatory indices and mortality risk in heart failure: a retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Prediction of prognosis in elderly patients with chronic heart failure based on random survival forest.Frontiers in cardiovascular medicine · 2025Article
- Impact of chest computed tomography-determined low skeletal muscle mass on the survival of patients with acute heart failure.Frontiers in cardiovascular medicine · 2025Article
- Association between red cell distribution width-to-albumin ratio and all-cause mortality in critically ill cirrhotic patients with sepsis: a retrospective analysis of the MIMIC-IV database.Frontiers in medicine · 2025Article
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15 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHypoalbuminemia is common in heart failure (HF) patients; however, there are no data regarding the possible long-term prognostic role of serum albumin (SA) in the younger population with chronic HF without malnutrition. The aim of this study was to examine the long-term prognostic role of SA levels in predicting major adverse cardiac events (MACE) in middle-aged outpatients with chronic HF.
methodsIn the present retrospective analysis, 378 subjects with HF were enrolled. MACE (non-fatal ischemic stroke, non-fatal myocardial infarction, cardiac revascularization or coronary bypass surgery, and cardiovascular death), total mortality, and HF hospitalizations (hHF) occurrence were evaluated during a median follow-up of 6.1 years.
resultsIn all population, 152 patients had a SA value < 3.5 g/dL and 226 had a SA value ≥ 3.5 g/dL. In patients with SA ≥ 3.5 g/dL, the observed MACE were 2.1 events/100 patient-year; while in the group with a worse SA levels, there were 7.0 events/100 patient-year (p < 0.001). The multivariate analysis model confirmed that low levels of SA increase the risk of MACE by a factor of 3.1. In addition, the presence of ischemic heart disease, serum uric acid levels > 6.0 mg/dL, chronic kidney disease, and a 10-year age rise, increased the risk of MACE in study participants. Finally, patients with SA < 3.5 g/dl had a higher incidence of hHF (p < 0.001) and total mortality (p < 0.001) than patients with SA ≥ 3.5 g/dl.
conclusionsPatients with chronic HF that exhibits low SA levels show a higher risk of MACE, hHF and total mortality.
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