Evidence map›Paper›PMID 38776000›Full record

ReviewCurrent environmental health reports2024

Portable x-ray fluorescence for bone lead measurement: Current approaches and future directions.

Aaron J Specht, Christian Hoover, Thomas Grier

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current environmental health reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aaron J SpechtSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN, 47907, USA. aspecht@purdue.edu.
Christian HooverDepartment of Epidemiology, Brown School of Public Health, Providence, RI, USA.
Thomas GrierSchool of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN, 47907, USA.

Funding

K01 Mentored Research Scientist Development AwardK01OH012528 · OH · PURDUE UNIVERSITY · PI SPECHT, AARON JAMES · 2023 to 2023
$180k
DoD CRMP 12971061NIOSH CDC HHS K01OH012528
6 · The paper itself

Abstract

purpose of reviewLegacy lead exposures persist as a widespread problem. Blood lead is traditionally used for lead exposure surveillance; however, bone lead proves to be a cheaper, more accessible, and more revealing tool for surveillance that can be measured using portable x-ray fluorescence techniques. We outline how this approach excels for bone lead measurements. RECENT

findingsPortable XRF offers quick, non-invasive in vivo quantification of bone lead. Compared to traditional KXRF systems, pXRF is limited to cortical bone but allows for quicker and similar results. Current methodologies of lead exposure need re-evaluation as lead-related disease burden and trends are dependent on both cumulative and acute impacts. We examined the evolution of XRF techniques for measuring bone lead, comparing current methods with previous ones. We assessed their accuracy, identified limitations, and discussed potential advances in future techniques. Legacy lead exposures call for a revitalization of lead surveillance methods, and pXRF measurement of bone lead offers such a solution.

Indexed as

Bone and BonesLeadSpectrometry, X-Ray EmissionEnvironmental ExposureEnvironmental MonitoringHumansLead PoisoningLeadHeavy MetalsIn vivo quantificationPortableSurveillanceX-ray fluorescence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.