Evidence map›Paper›PMID 38775936›Full record

ArticleMolecular biotechnology2025

Omaveloxolone Prevents Polystyrene Microplastic-Induced Ovarian Granulosa Cell Apoptosis via the Keap1/Nrf2/HO-1 Pathway in Rats.

Bing Li, Shu Tan, Xi Yu, Yan Wang

Abstract read
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In one paragraph

Article in Molecular biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bing LiDepartment of Gynaecology, Harbin Medical University Cancer Hospital, No.150, Haping Road, Nangang District, Harbin, Heilongjiang, 150081, China. libingjn331@163.com.ORCID http://orcid.org/0009-0000-7620-2600
Shu TanDepartment of Gynaecology, Harbin Medical University Cancer Hospital, No.150, Haping Road, Nangang District, Harbin, Heilongjiang, 150081, China.
Xi YuDepartment of Gynaecology, Harbin Medical University Cancer Hospital, No.150, Haping Road, Nangang District, Harbin, Heilongjiang, 150081, China.
Yan WangDepartment of Gynaecology, Harbin Medical University Cancer Hospital, No.150, Haping Road, Nangang District, Harbin, Heilongjiang, 150081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastics (MPs) are persistent environmental pollutants that enter the circulatory system and subsequently reduce sperm quantity and quality. However, the influence of polystyrene MPs (PS-MPs) on the ovary and relevant mechanisms remain elusive. Herein, we aimed to examine the impact of PS-MPs on oxidative disorders in ovarian tissues and elucidate the underlying mechanisms. Healthy female rats were treated with different concentrations of 0.5 µm PS-MPs (diluted in deionized H

Indexed as

ApoptosisGranulosa CellsPolystyrenesAnimalsFemaleHeme Oxygenase (Decyclizing)Kelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Oxidative StressRatsRats, Sprague-DawleySignal TransductionHeme Oxygenase (Decyclizing)Hmox1 protein, ratKEAP1 protein, ratKelch-Like ECH-Associated Protein 1Nfe2l2 protein, ratNF-E2-Related Factor 2PolystyrenesGranulosa cellsKeap1/Nrf2/HO-1 pathwayMicroplasticsOmaveloxoloneOvarian tissueOxidative stress

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.