Evidence map›Paper›PMID 38775902›Full record

ArticleJournal of epidemiology and global health2024

Cause-Specific Excess Mortality During the COVID-19 Pandemic (2020-2021) in 12 Countries of the C-MOR Consortium.

Victoria Virginia Beeks, Souzana Achilleos, Annalisa Quattrocchi, Chryso Th Pallari, Elena Critselis, Pascale Salameh, Mohammad Reza Rahmanian Haghighi, Jose Manuel Rodriguez-Llanes, Giuseppe Ambrosio, Andreas Artemiou and 22 more

Abstract read
In one paragraph

Article in Journal of epidemiology and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Victoria Virginia BeeksDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus. beeksvictoria@gmail.com.ORCID http://orcid.org/0009-0004-2808-491X
Souzana AchilleosDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0000-0002-1688-9225
Annalisa QuattrocchiDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0000-0002-5764-6721
Chryso Th PallariDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0000-0001-6781-9684
Elena CritselisDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0000-0001-5327-3510
Pascale SalamehDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Mohammad Reza Rahmanian HaghighiDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Jose Manuel Rodriguez-LlanesPlanAdapt, Berlin, Germany.ORCID http://orcid.org/0000-0003-3736-736X
Giuseppe AmbrosioDepartment of Cardiology, University of Perugia School of Medicine, Perugia, Italy.ORCID http://orcid.org/0000-0002-8001-8627
Andreas ArtemiouDepartment of Information Technologies, University of Limassol, Limassol, Cyprus.ORCID http://orcid.org/0000-0002-7501-4090
John GabelMassachusetts Institute of Technology, Cambridge, MA, USA.
Catherine Marie BennettSchool of Health and Social Development, Institute for Health Transformation, Deakin University, Waurn Ponds, Australia.ORCID http://orcid.org/0000-0001-9581-1612
Joseph CuthbertsonMonash University Disaster Resilience Initiative, Monash University, Melbourne, Australia.
Claudia ZimmermannDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-2751-6926
Eva Susanna SchernhammerDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-4337-9415
Antonio José Leal CostaInstituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-0402-4865
Luciana Freire de CarvalhoInstituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Jackeline Christiane Pinto LobatoDepartamento de Epidemiologia do Instituto de Saúde Coletiva, Universidade Federal Fluminense, Niterói, Brazil.
Maria AthanasiadouHealth Monitoring Unit, Cyprus Ministry of Health, 1 Prodromou & 17 Chilonos Street, 1448, Nicosia, Cyprus.
Julia Alison CritchleyPopulation Health Research Institute, St George's University of London, London, UK.ORCID http://orcid.org/0000-0002-5248-4188
Lucy Pollyanna GoldsmithPopulation Health Research Institute, St George's University of London, London, UK.ORCID http://orcid.org/0000-0002-6934-1925
Levan KandelakiMedical Statistics, National Center for Disease Control and Public Health, Tbilisi, Georgia.
Natalya GlushkovaHealth Research Institute, Al-Farabi Kazakh National University, Almaty, Kazakhstan.ORCID http://orcid.org/0000-0003-1400-8436
Kairat DavletovAsfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.ORCID http://orcid.org/0000-0001-8534-1899
Yuliya SemenovaSchool of Medicine, Nazarbayev University, Astana, Kazakhstan.ORCID http://orcid.org/0000-0003-1324-7806
Ivan ErzenSchool of Public Health, National Institute of Public Health, Ljubljana, Slovenia.
Olesia VerstiukDepartment of Medical Science, University of Nicosia, Nicosia, Cyprus.ORCID http://orcid.org/0000-0002-0557-8923
Dimos AlekkouDepartment of Psychology, University of Nicosia, Nicosia, Cyprus.
Antonis PolemitisUniversity of Nicosia, Nicosia, Cyprus.
Andreas CharalambousUniversity of Nicosia Medical School, Nicosia, Cyprus.
Christiana A DemetriouDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.ORCID http://orcid.org/0000-0003-4002-2880
C-MOR Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated cause-specific mortality rates in 12 countries during the COVID-19 pandemic in 2020 and 2021.

methodsWe collected weekly cause-specific mortality data from respiratory disease, pneumonia, cardiovascular disease (CVD) and cancer from national vital statistic databases. We calculated excess mortality for respiratory disease (excluding COVID-19 codes), pneumonia, and CVD in 2020 and 2021 by comparing observed weekly against expected mortality based on historical data (2015-2019), accounting for seasonal trends. We used multilevel regression models to investigate the association between country-level pandemic-related variables and cause-specific mortality.

resultsSignificant reductions in cumulative mortality from respiratory disease and pneumonia were observed in 2020 and/or 2021, except for Georgia, Northern Ireland, Kazakhstan, and Ukraine, which exhibited excess mortality for one or both causes. Australia, Austria, Cyprus, Georgia, and Northern Ireland experienced excess cumulative CVD mortality in 2020 and/or 2021. Australia, Austria, Brazil, Cyprus, Georgia, Northern Ireland, Scotland and Slovenia, experienced increased crude cumulative cancer mortality during 2020 and/or 2021 compared to previous years. Among pandemic-related variables, reported COVID-19 incidence was negatively associated with increased cancer mortality, excess respiratory, (2020) and pneumonia (2021) mortality, and positively associated with respiratory and CVD mortality (2021). Stringency of control measures were negatively associated with excess respiratory disease, CVD, and increased cancer mortality (2021).

conclusionsThis study provides evidence of substantial excess mortality from CVD, and notable reductions in respiratory disease and pneumonia in both years across most countries investigated. Our study also highlights the beneficial impact of stringent control measures in mitigating excess mortality from most causes in 2021.

Indexed as

Cardiovascular DiseasesCause of DeathCOVID-19NeoplasmsAustraliaGlobal HealthHumansMaleMortalityPandemicsPneumoniaRespiratory Tract DiseasesSARS-CoV-2CancerCardiovascular diseasesCause-specific mortalityCOVID-19Public health measuresRespiratory tract infections

Identifiers

PMID38775902
PMCPMC11176135

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.