Evidence map›Paper›PMID 38775901›Full record

ArticleJournal of epidemiology and global health2024

Predictors of HIV Viral Load Suppression After Enhanced Adherence Counseling, Nekemte, Ethiopia.

Yohannis Mosisa, Adisu Ewunetu, Kitesa Biresa Duftu, Bayise Biru, Debelo Diriba, Adisu Tafari Shama, Melese Lemi, Getahun Fetensa, Bikila Regassa Feyisa

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Article in Journal of epidemiology and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yohannis MosisaWallaga University Comprehensive Specialized Hospital, Nekemte, Ethiopia.
Adisu EwunetuDepartment of Public Health, Institute of Health Sciences, Wallaga University, Nekemte, Ethiopia.
Kitesa Biresa DuftuDepartment of Epidemiology, Faculty of Public Health, Institute of Health, Jimma University, Nekemte, Ethiopia. qmhiriyaa@gmail.com.ORCID 0009-0008-5045-1682
Bayise BiruDepartment of Public Health, Institute of Health Sciences, Wallaga University, Nekemte, Ethiopia.
Debelo DiribaFood for the Hungry Ethiopia, Western Region, Nekemte, Ethiopia.
Adisu Tafari ShamaDepartment of Public Health, Institute of Health Sciences, Wallaga University, Nekemte, Ethiopia.
Melese LemiEarly Warning and Preparedness Case Team, Public Health Emergency Management and Health Research Directorate, Oromia Health Bureau, Oromia, Ethiopia.
Getahun FetensaDepartment of Nursing, School of Nursing and Midwifery, Institute of Health Sciences, Wallaga University, Nekemte, Ethiopia.
Bikila Regassa FeyisaDepartment of Public Health, Institute of Health Sciences, Wallaga University, Nekemte, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced adherence counseling refers to the counseling intervention for Human Immunodeficiency Virus (HIV) patients with an elevated viral load result, a viral load of > 1000 copies/ml, on a routine or need-based viral load test. The Federal Ministry of Health, Ethiopia, has launched routine viral load testing and enhanced adherence counseling since 2016 for high-viral load people living with HIV, which is applicable throughout the country for all health facilities providing HIV care and treatment. Our study aimed to assess viral load suppression after enhanced adherence counseling and its predictors among high viral load people living with HIV who were on antiretroviral therapy.

methodWe conducted a health facility-based retrospective follow-up study among 352 HIV-infected high-viral load people enrolled in enhanced adherence counseling from July 2018 to June 2021 in Nekemte town public health facilities. Cox proportional hazard analysis was used to identify independent predictors.

resultsThe overall 65.1% of 352 persons on antiretroviral treatment achieved HIV viral load suppression after enhanced adherence counseling, (15.01 per 100 person months (95% CI13.02-16.99)). The median time to viral load suppression was 5 months. Age ≥ 15 years (AHR = 1.99, 95% CI: 1.11-3.57), no history of opportunistic infection (AHR = 2.01, 95% CI: 1.18-3.41), and not using substances (AHR = 2.48, 95% CI: 1.19-5.14) were more likely to have viral load suppressed, while having an initial viral load count greater than 50,000 RNA copies/ml (AHR = 0.56, 95% CI: 0.37-0.85) were less likely to have viral load suppressed after enhanced adherence counseling.

conclusionAge, history of opportunistic infections, substance use, and an initial viral load count > 50,000 RNA copies/mL were significant predictors of viral load suppression. Enrolling all high-viral-load patients in enhanced adherence counseling is recommended for viral load suppression.

Indexed as

CounselingDrug MonitoringHIV InfectionsViral LoadAdolescentAdultAnti-HIV AgentsEthiopiaFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesYoung AdultAnti-HIV AgentsEnhanced adherence counselingNekemte townPublic health facilitiesViral load suppression

Identifiers

PMID38775901
PMCPMC11442734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.