Evidence map›Paper›PMID 38775807›Full record

ArticleJournal of applied clinical medical physics2024

The delivery assessment for small targets on Halcyon radiotherapy system - Measured and calculated dose comparison.

Linda Lankinen, Antti Kulmala, Jouko Lehtomäki, Ari Harju

Abstract readComparative Study
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Linda LankinenVarian Medical Systems, a Siemens Healthineers Company, Helsinki, Finland.ORCID https://orcid.org/0000-0003-2625-1070
Antti KulmalaClinical Research Institute HUCH Ltd., Helsinki, Finland.
Jouko LehtomäkiVarian Medical Systems, a Siemens Healthineers Company, Helsinki, Finland.
Ari HarjuVarian Medical Systems, a Siemens Healthineers Company, Helsinki, Finland.

Funding

A Siemens Healthineers CompanyVarian Medical Systems
6 · The paper itself

Abstract

backgroundWith the ever-increasing requirements of accuracy and personalization of radiotherapy treatments, stereotactic radiotherapy (SRT) with volumetric modulated arc therapy (VMAT) on O-ring Halcyon radiotherapy system could potentially provide a fast, safe, and feasible treatment option. PURPOSE: The purpose of this study was to assess the delivery of Halcyon VMAT plans for small targets.

methodsWell-defined VMAT-SRT plans were created on Halcyon radiotherapy system with the stacked and staggered dual-layer MLC design for the film measurement set-up and the target sizes and shapes designed to emulate the targets of the stereotactic treatments. The planar dose distributions were acquired with film measurements and compared to a current clinical reference dose calculation with AcurosXB (v18.0, Varian Medical Systems) and to Monte Carlo simulations. With the collapsed arc versions of the VMAT-SRT plans, the uncertainty in dose delivery due to the multileaf collimator (MLC) without the gantry rotation could be separated and analyzed.

resultsThe target size was mainly limited by the resolution originated from the design of the MLC leaves. The results of the collapsed arc versions of the plans show good consistency among measured, calculated, and simulated dose distributions. With the full VMAT plans, the agreement between calculated and simulated dose distributions was consistent with the collapsed arc versions. The measured dose distribution agreed with the calculated and simulated dose distributions within the target regions, but considerable local differences were observed in the margins of the target. The largest differences located in the steep gradient regions presumably originating from the deviation of the isocenter.

conclusionsThe potential of the Halcyon radiotherapy system for VMAT-SRT delivery was evaluated and the study revealed valuable insights on the machine characteristics with the delivery.

Indexed as

Monte Carlo MethodOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansNeoplasmsParticle AcceleratorsPhantoms, ImagingRadiosurgeryHalcyonMonte Carlosmall fieldstereotacticVMAT

Identifiers

PMID38775807
PMCPMC11163489

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.