Evidence map›Paper›PMID 38775645›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2024

How to harvest the left internal mammary artery-a randomized controlled trial.

Sofie Laugesen, Lytfi Krasniqi, Leila Louise Benhassen, Poul Erik Mortensen, Peter Appel Pallesen, Søren Bak, Bo Juel Kjelsen, Lars Peter Riber

Registry-linked trialAbstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05562908 (Skeletonised Versus Pedicled Internal Thoracic Artery - A Randomised Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05562908 nacompletednot on this map

Skeletonised Versus Pedicled Internal Thoracic Artery - A Randomised Study

TypeinterventionalSponsorLars Peter RiberRan2019 to 2021Enrolled165ConditionsHeart DiseasesArmsPedicled, Surgical skeletonised, Thunderbeat skeletonised
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The History of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sofie LaugesenDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-3024-9347
Lytfi KrasniqiDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.
Leila Louise BenhassenDepartment of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.
Poul Erik MortensenDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.
Peter Appel PallesenDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.
Søren BakDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.
Bo Juel KjelsenDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.
Lars Peter RiberDepartment of Cardio, Vascular and Thoracic Surgery, Odense University Hospital, Odense, Denmark.

Funding

Odense University HospitalRegion of Southern Denmark
6 · The paper itself

Abstract

objectivesIt is uncertain whether Thunderbeat has a place in harvesting the left internal mammary artery (LIMA) and whether skeletonization is superior to pedicle-harvested LIMA. Some investigations have shown improved flowrates in the skeletonized graft. The aim of this study was to compare 3 groups of harvesting techniques: Pedicled, surgical skeletonized and skeletonized with Thunderbeat in terms of flow rates in the LIMA and postoperative in-hospital outcomes.

methodsPatients undergoing coronary artery bypass grafting with the LIMA to the anterior descending artery were randomized to pedicled (n = 56), surgical skeletonized (n = 55) and skeletonized with Thunderbeat (n = 54). Main outcomes were blood flow and pulsatility index in the graft.

resultsNo statistical difference between groups regarding flow in LIMA or pulsatility index. Similarly, no difference in postoperative bleeding or days of hospitalization. The duration of harvesting was faster for the pedicled technique compared with surgical skeletonized and skeletonized with Thunderbeat [mean total min: pedicled 20.2 min standard deviation (SD) ± 5.4; surgical skeletonized 28.6 min SD ± 8.7; skeletonized with Thunderbeat 28.3 min SD ± 9.11, P < 0.001]. No grafts discarded due to faulty harvesting and there was no graft failure within hospital stay.

conclusionsWe found no difference between the harvesting methods except for a significantly faster harvesting time with the pedicled technique. However, non-touch skeletonized LIMA harvesting with Thunderbeat seems to be an effective alternative to traditional surgical skeletonized LIMA. The future will reveal whether patency is harvesting dependent. CLINICAL

trial registrationClinicalTrials.gov Identifier: NCT05562908.

Indexed as

Coronary artery bypassflowGraft-harvestingLeft internal mammary artery

Identifiers

PMID38775645
PMCPMC11139514

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.