Evidence map›Paper›PMID 38775535›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2024

Are monocyte-to-HDL and C-reactive protein-to-albumin ratios useful for the diagnosis and follow-up of Takayasu arteritis?

Elif Altunel Kılınç, Gizem Varkal, Gizem Kırmızıer, İpek Türk, Hüseyin Turgut Elbek Özer

Abstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Elif Altunel KılınçÇukurova University, Faculty of Medicine, Department of Rheumatology - Adana, Turkey.ORCID http://orcid.org/0000-0003-2501-2473
Gizem VarkalÇukurova University, Faculty of Medicine, Department of Rheumatology - Adana, Turkey.ORCID http://orcid.org/0000-0003-2270-102X
Gizem KırmızıerÇukurova University, Faculty of Medicine, Department of Rheumatology - Adana, Turkey.ORCID http://orcid.org/0000-0003-0092-8645
İpek TürkÇukurova University, Faculty of Medicine, Department of Rheumatology - Adana, Turkey.ORCID http://orcid.org/0000-0001-5192-9045
Hüseyin Turgut Elbek ÖzerÇukurova University, Faculty of Medicine, Department of Rheumatology - Adana, Turkey.ORCID http://orcid.org/0000-0003-0256-4611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this study, we aimed to investigate the role of erythrocyte sedimentation rate, C-reactive protein, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, monocyte/lymphocyte ratio, red blood cell distribution width, mean platelet volume, monocyte/HDL ratio, and C-reactive protein/albumin ratio in the diagnosis and treatment follow-up of active and remission Takayasu arteritis patients compared with healthy control group.

methodsThis is a retrospective case-control study in which 56 Takayasu arteritis patients and 40 age- and sex-matched healthy control were included. The blood values of Takayasu arteritis patients were analyzed during their active period and post-treatment remission periods, after comparing them with the healthy control. Furthermore, all parameters were evaluated by receiver operating characteristic analysis.

resultsErythrocyte sedimentation rate, C-reactive protein, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, monocyte/lymphocyte ratio, monocyte/HDL ratio, and C-reactive protein/albumin ratio values were significantly higher in active Takayasu arteritis patients compared with healthy control and remission Takayasu arteritis groups. In the receiver operating characteristic analysis performed in active Takayasu arteritis and Takayasu arteritis patients in remission, C-reactive protein had the highest power to indicate disease activity, followed by C-reactive protein/albumin ratio, erythrocyte sedimentation rate, and monocyte/HDL ratio. When Takayasu arteritis in remission was compared with the healthy control, a significant difference was found between erythrocyte sedimentation rate, C-reactive protein, red blood cell distribution width, and C-reactive protein/albumin ratio, while no significant difference was found between monocyte/HDL ratio values.

conclusionC-reactive protein/albumin ratio and red blood cell distribution width can be used in the diagnosis of Takayasu arteritis, and C-reactive protein/albumin ratio, red blood cell distribution width, and monocyte/HDL ratio measurements can be used in the follow-up. As C-reactive protein/albumin ratio is more powerful than C-reactive protein in differentiating the Takayasu arteritis group from the healthy control group, evaluation of C-reactive protein/albumin ratio together with albumin instead of evaluation of C-reactive protein alone when diagnosing the disease may help us to obtain more accurate results in daily practice.

Indexed as

Blood SedimentationC-Reactive ProteinMonocytesTakayasu ArteritisAdolescentAdultBiomarkersCase-Control StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesROC CurveSerum AlbuminBiomarkersC-Reactive ProteinSerum Albumin

Identifiers

PMID38775535
PMCPMC11101177

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