Evidence map›Paper›PMID 38775452›Full record

SynthesisJournal of the International Society of Sports Nutrition2024

Association of low muscle mass index and sarcopenic obesity with knee osteoarthritis: a systematic review and meta-analysis.

Qiming Wu, Zhuyan Xu, Xiaomin Ma, Juan Li, Jun Du, Jing Ji, Xiaomeng Ling, Juntao Kan, Min Zhao

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the International Society of Sports Nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07161895 (Prevalence of Kinesiophobia and Its Effects on Functional Capacity and Pain Severity in Patients With Primary Knee Osteoarthritis), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07161895 completednot on this mapstarted 2025, after this paper: background citation

Prevalence of Kinesiophobia and Its Effects on Functional Capacity and Pain Severity in Patients With Primary Knee Osteoarthritis

TypeobservationalSponsorAnkara Training and Research HospitalRan2025 to 2026Enrolled84ConditionsKnee Osteoarthritis (Knee OA), OA, Kinesiophobia
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Identification of shared key genes and pathways in osteoarthritis and sarcopenia patients based on bioinformatics analysis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qiming WuNutrilite Health Institute, Shanghai, China.
Zhuyan XuShandong University, Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Jinan, China.
Xiaomin MaShandong University, Experimental center for public health and Preventive Medicine, School of Public Health, Cheeloo College of Medicine, Jinan, Shandong, China.
Juan LiShandong University, Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Jinan, China.
Jun DuNutrilite Health Institute, Shanghai, China.
Jing JiShandong University, Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Jinan, China.
Xiaomeng LingShandong University, Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Jinan, China.
Juntao KanNutrilite Health Institute, Shanghai, China.
Min ZhaoShandong University, Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia and knee osteoarthritis are common age-related diseases that have become important public health issues worldwide. Few studies have reported the association between muscle mass loss and knee osteoarthritis. This may be due to the high level of heterogeneity between studies stemming from different definitions of muscle mass loss.

methodsThe systematic searches were carried out in PubMed and Web of Science from the inception of the databases until 13 January 2023, by two independent researchers. Pooled odds ratios (ORs) for overall and subgroup analyses were obtained using either a random effects model (I

resultsOf the 1,606 studies identified, we ultimately included 12 articles on the association between muscle mass and knee osteoarthritis (prospective:

conclusionThis systematic review and meta-analysis revealed that low muscle mass index and sarcopenic obesity were associated with an increased risk of developing knee osteoarthritis.

Indexed as

ObesityOsteoarthritis, KneeSarcopeniaHumansMuscle, Skeletalknee osteoarthritismeta-analysismuscle massSarcopeniasystematic review

Identifiers

PMID38775452
PMCPMC11123550

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.