Evidence map›Paper›PMID 38775129›Full record

ArticleJournal of athletic training2025

Clinical Features Post-Anterior Cruciate Ligament Reconstruction Associated With Structural Alterations in the Corticospinal Tract.

Le Yu, Zhengbiao Jin, Xiao'ao Xue, Weichu Tao, Xiaoyun Xu, Tian Xia, Yuwen Zhang, Wenwen Yu, Ru Wang, He Wang and 1 more

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Article in Journal of athletic training, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Le YuDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Zhengbiao JinDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xiao'ao XueDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Weichu TaoSchool of Exercise and Health, Shanghai University of Sport, China.
Xiaoyun XuSchool of Exercise and Health, Shanghai University of Sport, China.
Tian XiaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Yuwen ZhangDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Wenwen YuInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.
Ru WangSchool of Exercise and Health, Shanghai University of Sport, China.
He WangInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.
Yinghui HuaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextStructural evidence for corticospinal tract (CST) abnormality in patients with anterior cruciate ligament reconstruction (ACLR) compared with healthy controls and the relationships between CST structure and clinical features of the patients (eg, objective sensorimotor outcomes and postoperative duration) are lacking.

objectiveTo investigate whether the structural features of the CST differ between patients with ACLR and healthy controls and are associated with clinical features in patients after ACLR.

designCross-sectional study.

settingSports medicine laboratory. PATIENTS OR OTHER

participantsA total of 26 patients who had undergone ACLR (age = 36.35 ± 6.39 years, height = 173.88 ± 5.97 cm, mass = 74.80 ± 10.61 kg) and 26 healthy controls (age = 32.85 ± 9.20 years, height = 173.35 ± 7.19 cm, mass = 72.88 ± 11.06 kg) participated. MAIN OUTCOME MEASURE(S): Using the CST as the region of interest, we performed diffusion tensor imaging to measure the microstructure of white matter tracts. Between-groups comparisons and correlation analyses with clinical features in patients with ACLR were performed.

resultsPatients with ACLR had moderately lower fractional anisotropy (Cohen d = -0.666; 95% CI = -1.221, -0.104; P = .01), lower axial diffusivity (Cohen d = -0.526; 95% CI = -1.077, 0.030; P = .03), higher radial diffusivity (RD; Cohen d = 0.514; 95% CI = -0.042, 1.064; P = .04), and smaller Y-Balance Test anterior-reach distance (Cohen d = -0.743; 95% CI = -1.302, -0.177; P = .005) compared with healthy controls. The RD values were correlated with the postoperative duration (r = 0.623, P < .001) after controlling for age, sex, and body mass index in patients with ACLR.

conclusionsPatients with ACLR had impaired integrity (lower fractional anisotropy values and higher RD values) in the CST contralateral to the ACLR injured limb in comparison with healthy controls. Decreased integrity (higher RD) of the CST in patients was associated with longer postoperative duration, which hinted that impaired structural integrity of the CST may be a maladaptive process of neuroplasticity in ACLR.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionPyramidal TractsAdultAnisotropyCase-Control StudiesCross-Sectional StudiesDiffusion Tensor ImagingFemaleHumansMaleYoung Adultdiffusion tensor imagingneuroplasticitypostoperative durationsensorimotor deficit

Identifiers

PMID38775129
PMCPMC12057743

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