Evidence map›Paper›PMID 38774953›Full record

ArticleLupus2024

Evaluation of depressive and anxiety symptoms in childhood-onset systemic lupus erythematosus: Frequency, course, and associated risk factors.

Kate M Neufeld, Paris Moaf, Michelle Quilter, Ashley N Danguecan, Julie Couture, Daniela Dominguez, Olivia Hendrikx, Lawrence Ng, Reva Schachter, Daphne D Korczak and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lupus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kate M NeufeldDivision of Pediatric Rheumatology, Department of Pediatrics, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.ORCID 0000-0002-6872-1758
Paris MoafDepartment of Neurosciences and Mental Health, Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Michelle QuilterDepartment of Psychiatry, Whyteman's Brae Hospital, NHS Fife, Kirkaldy, Scotland.
Ashley N DanguecanDepartment of Psychology, The Hospital for Sick Children, Toronto, ON, Canada.
Julie CoutureDivision of Pediatric Rheumatology, Department of Pediatrics, Centre mère-enfant Soleil du CHU de Québec, Laval University, Quebec City, QC, Canada.
Daniela DominguezDivision of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Olivia HendrikxDepartment of Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada.
Lawrence NgDivision of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Reva SchachterDivision of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.
Daphne D KorczakDepartment of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.
Deborah M LevyDivision of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Linda HirakiDivision of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Andrea M KnightDivision of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepressive and anxiety symptoms are common in childhood-onset systemic lupus erythematosus (cSLE), yet their etiology and course remain unclear. We investigated the frequency of depressive and anxiety symptoms longitudinally in youth with cSLE, and associated socio-demographic and disease factors.

methodsParticipants 8-18 years with cSLE completed baseline measures [demographic questionnaire, Center for Epidemiologic Studies Depression Scale for Children (CES-DC), Screen for Childhood Anxiety Related Disorders (SCARED), and psychiatric interview] and follow-up measures (CES-DC and SCARED) > 6 months later. Prevalence of clinically significant depressive (score >15 on CES-DC) or anxiety symptoms (score

resultsAt baseline, of 51 participants with a mean disease duration of 4.3 years (SD 2.7), 35% (

conclusionIn this sample, depressive and anxiety symptoms were prevalent and persistent. Depressive symptoms correlated with neighborhood-level material deprivation, and family psychiatric history. These findings support routine psychosocial assessment in cSLE, and provision of appropriate resources.

Indexed as

AnxietyDepressionLupus Erythematosus, SystemicAdolescentAge of OnsetAnxiety DisordersChildFemaleHumansLongitudinal StudiesMalePrevalencePsychiatric Status Rating ScalesRisk FactorsSurveys and QuestionnairesanxietyDepressionpediatricpsychosocial healthscreeningsystemic lupus erythematosus

Identifiers

PMID38774953
PMCPMC11141111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.